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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

3P0Y

anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
ChainResidueDetails
LTYR192-HIS198
HTYR194-HIS200
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10731668","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12297049","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12297050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12620237","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12731890","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16083266","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20837704","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MOX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NQL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B2V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P0Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UV7","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10731668","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12297050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12620237","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12731890","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16083266","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20837704","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NQL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UV7","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12731890","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16083266","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8962717","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B2V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P0Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRP","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12297050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12620237","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12731890","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16083266","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20837704","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8962717","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NQL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B2V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P0Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UV7","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

243531

PDB entries from 2025-10-22

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