3OPY
Crystal structure of Pichia pastoris phosphofructokinase in the T-state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003872 | molecular_function | 6-phosphofructokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005945 | cellular_component | 6-phosphofructokinase complex |
| A | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016208 | molecular_function | AMP binding |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048029 | molecular_function | monosaccharide binding |
| A | 0061621 | biological_process | canonical glycolysis |
| A | 0070095 | molecular_function | fructose-6-phosphate binding |
| B | 0003872 | molecular_function | 6-phosphofructokinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005945 | cellular_component | 6-phosphofructokinase complex |
| B | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016208 | molecular_function | AMP binding |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048029 | molecular_function | monosaccharide binding |
| B | 0061621 | biological_process | canonical glycolysis |
| B | 0070095 | molecular_function | fructose-6-phosphate binding |
| C | 0003872 | molecular_function | 6-phosphofructokinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005945 | cellular_component | 6-phosphofructokinase complex |
| C | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016208 | molecular_function | AMP binding |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016310 | biological_process | phosphorylation |
| C | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0048029 | molecular_function | monosaccharide binding |
| C | 0061621 | biological_process | canonical glycolysis |
| C | 0070095 | molecular_function | fructose-6-phosphate binding |
| D | 0003872 | molecular_function | 6-phosphofructokinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005945 | cellular_component | 6-phosphofructokinase complex |
| D | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016208 | molecular_function | AMP binding |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016310 | biological_process | phosphorylation |
| D | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0048029 | molecular_function | monosaccharide binding |
| D | 0061621 | biological_process | canonical glycolysis |
| D | 0070095 | molecular_function | fructose-6-phosphate binding |
| E | 0003872 | molecular_function | 6-phosphofructokinase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0005945 | cellular_component | 6-phosphofructokinase complex |
| E | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| E | 0006096 | biological_process | glycolytic process |
| E | 0016208 | molecular_function | AMP binding |
| E | 0016301 | molecular_function | kinase activity |
| E | 0016310 | biological_process | phosphorylation |
| E | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0048029 | molecular_function | monosaccharide binding |
| E | 0061621 | biological_process | canonical glycolysis |
| E | 0070095 | molecular_function | fructose-6-phosphate binding |
| F | 0003872 | molecular_function | 6-phosphofructokinase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005739 | cellular_component | mitochondrion |
| F | 0005945 | cellular_component | 6-phosphofructokinase complex |
| F | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| F | 0006096 | biological_process | glycolytic process |
| F | 0016208 | molecular_function | AMP binding |
| F | 0016301 | molecular_function | kinase activity |
| F | 0016310 | biological_process | phosphorylation |
| F | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| F | 0042802 | molecular_function | identical protein binding |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0048029 | molecular_function | monosaccharide binding |
| F | 0061621 | biological_process | canonical glycolysis |
| F | 0070095 | molecular_function | fructose-6-phosphate binding |
| G | 0003872 | molecular_function | 6-phosphofructokinase activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005739 | cellular_component | mitochondrion |
| G | 0005945 | cellular_component | 6-phosphofructokinase complex |
| G | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| G | 0006096 | biological_process | glycolytic process |
| G | 0016208 | molecular_function | AMP binding |
| G | 0016301 | molecular_function | kinase activity |
| G | 0016310 | biological_process | phosphorylation |
| G | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| G | 0042802 | molecular_function | identical protein binding |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0048029 | molecular_function | monosaccharide binding |
| G | 0061621 | biological_process | canonical glycolysis |
| G | 0070095 | molecular_function | fructose-6-phosphate binding |
| H | 0003872 | molecular_function | 6-phosphofructokinase activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005739 | cellular_component | mitochondrion |
| H | 0005945 | cellular_component | 6-phosphofructokinase complex |
| H | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| H | 0006096 | biological_process | glycolytic process |
| H | 0016208 | molecular_function | AMP binding |
| H | 0016301 | molecular_function | kinase activity |
| H | 0016310 | biological_process | phosphorylation |
| H | 0030388 | biological_process | fructose 1,6-bisphosphate metabolic process |
| H | 0042802 | molecular_function | identical protein binding |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0048029 | molecular_function | monosaccharide binding |
| H | 0061621 | biological_process | canonical glycolysis |
| H | 0070095 | molecular_function | fructose-6-phosphate binding |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0006096 | biological_process | glycolytic process |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0006096 | biological_process | glycolytic process |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0006096 | biological_process | glycolytic process |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006096 | biological_process | glycolytic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ATP F 942 |
| Chain | Residue |
| F | ASP393 |
| F | ILE414 |
| F | PHE553 |
| F | ILE554 |
| F | ASN557 |
| F | SER558 |
| F | TYR394 |
| F | ILE395 |
| F | LYS400 |
| F | ALA402 |
| F | SER403 |
| F | SER404 |
| F | ARG405 |
| F | GLN410 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ATP D 942 |
| Chain | Residue |
| D | ASP393 |
| D | TYR394 |
| D | ILE395 |
| D | LYS400 |
| D | SER403 |
| D | SER404 |
| D | ARG405 |
| D | GLN410 |
| D | ILE414 |
| D | PHE553 |
| D | ILE554 |
| D | ASN557 |
| D | SER558 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ATP B 942 |
| Chain | Residue |
| B | ASP393 |
| B | TYR394 |
| B | ILE395 |
| B | LYS400 |
| B | SER403 |
| B | SER404 |
| B | ARG405 |
| B | GLN410 |
| B | ILE414 |
| B | PHE553 |
| B | ILE554 |
| B | ASN557 |
| B | SER558 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ATP H 942 |
| Chain | Residue |
| H | ASP393 |
| H | TYR394 |
| H | ILE395 |
| H | LYS400 |
| H | SER403 |
| H | SER404 |
| H | ARG405 |
| H | GLN410 |
| H | ILE414 |
| H | PHE553 |
| H | ILE554 |
| H | ASN557 |
| H | SER558 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 990 |
| Chain | Residue |
| A | GLY219 |
| A | GLY220 |
| A | GLY313 |
| A | ASP314 |
| A | GLY315 |
| A | SER316 |
| A | SO4991 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 991 |
| Chain | Residue |
| A | GLY220 |
| A | GLY358 |
| A | SER359 |
| A | ILE360 |
| A | ASP361 |
| A | ARG496 |
| A | SO4990 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 943 |
| Chain | Residue |
| A | MET403 |
| A | HIS493 |
| A | ARG496 |
| B | ARG368 |
| B | ARG460 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 992 |
| Chain | Residue |
| A | ARG635 |
| A | SO4993 |
| B | LYS797 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 993 |
| Chain | Residue |
| A | ARG635 |
| A | SO4992 |
| B | GLN793 |
| B | GLY794 |
| B | LYS797 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 994 |
| Chain | Residue |
| A | ALA608 |
| A | ARG670 |
| A | HIS864 |
| B | ARG739 |
| B | LYS832 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 995 |
| Chain | Residue |
| A | THR575 |
| A | ARG881 |
| A | LYS885 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 990 |
| Chain | Residue |
| A | GLY917 |
| E | ARG643 |
| E | HIS644 |
| F | ARG828 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 I 352 |
| Chain | Residue |
| I | ARG93 |
| I | ASP250 |
| I | THR251 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 I 353 |
| Chain | Residue |
| I | SER129 |
| I | LYS200 |
| I | ARG204 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 990 |
| Chain | Residue |
| C | ARG234 |
| C | GLY270 |
| C | LEU272 |
| C | LYS756 |
| C | ARG230 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 944 |
| Chain | Residue |
| B | ARG201 |
| B | ARG205 |
| B | ARG241 |
| B | GLY242 |
| B | LYS730 |
| B | GLY762 |
| B | SER798 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 996 |
| Chain | Residue |
| A | ARG230 |
| A | ARG234 |
| A | VAL268 |
| A | ARG269 |
| A | GLY270 |
| A | LEU272 |
| A | LYS756 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 943 |
| Chain | Residue |
| D | ARG201 |
| D | ARG205 |
| D | ARG241 |
| D | GLY242 |
| D | LYS730 |
| D | GLY762 |
| D | SER798 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 991 |
| Chain | Residue |
| C | SER359 |
| C | ILE360 |
| C | ASP361 |
| C | ARG496 |
| C | SO4992 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 G 990 |
| Chain | Residue |
| G | GLY358 |
| G | SER359 |
| G | ILE360 |
| G | ASP361 |
| G | ARG496 |
| G | SO4992 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 J 352 |
| Chain | Residue |
| J | GLY180 |
| J | PRO181 |
| J | HIS196 |
| J | LEU198 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 944 |
| Chain | Residue |
| C | ARG635 |
| C | SO4994 |
| D | GLN793 |
| D | GLY794 |
| D | LYS797 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 992 |
| Chain | Residue |
| C | GLY219 |
| C | GLY220 |
| C | GLY313 |
| C | ASP314 |
| C | GLY315 |
| C | SER316 |
| C | SO4991 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 945 |
| Chain | Residue |
| C | MET403 |
| C | HIS493 |
| C | ARG496 |
| D | ARG368 |
| D | ARG460 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 G 991 |
| Chain | Residue |
| G | ARG230 |
| G | ARG234 |
| G | ARG269 |
| G | GLY270 |
| G | LYS756 |
| G | GLY788 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 H 943 |
| Chain | Residue |
| H | ARG201 |
| H | ARG205 |
| H | ARG241 |
| H | GLY242 |
| H | LYS730 |
| H | GLY762 |
| H | SER798 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 993 |
| Chain | Residue |
| C | ALA608 |
| C | ARG670 |
| C | HIS864 |
| D | ARG739 |
| D | LYS832 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 F 943 |
| Chain | Residue |
| F | ARG201 |
| F | ARG205 |
| F | ARG241 |
| F | GLY242 |
| F | LYS730 |
| F | SER798 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 G 992 |
| Chain | Residue |
| G | GLY219 |
| G | GLY220 |
| G | GLY313 |
| G | ASP314 |
| G | GLY315 |
| G | SER316 |
| G | SO4990 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 H 944 |
| Chain | Residue |
| G | ARG635 |
| H | GLN793 |
| H | GLY794 |
| H | LYS797 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 991 |
| Chain | Residue |
| E | ALA608 |
| E | ARG670 |
| E | HIS864 |
| F | ARG739 |
| F | LYS832 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 H 945 |
| Chain | Residue |
| G | MET403 |
| G | HIS493 |
| G | ARG496 |
| H | ARG368 |
| H | ARG460 |
| site_id | DC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 K 352 |
| Chain | Residue |
| K | ARG93 |
| K | PHE249 |
| K | ASP250 |
| K | THR251 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 992 |
| Chain | Residue |
| E | SER359 |
| E | ILE360 |
| E | ASP361 |
| E | ARG496 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 997 |
| Chain | Residue |
| A | ARG324 |
| A | SER528 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 J 353 |
| Chain | Residue |
| J | SER129 |
| J | LYS200 |
| J | ARG204 |
| site_id | EC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 F 944 |
| Chain | Residue |
| E | MET403 |
| E | HIS493 |
| E | ARG496 |
| F | ARG368 |
| F | ARG460 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 998 |
| Chain | Residue |
| A | ARG670 |
| A | SER729 |
| A | ASN731 |
| A | GLY774 |
| A | LYS961 |
| site_id | EC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 E 993 |
| Chain | Residue |
| E | ARG230 |
| E | ARG234 |
| E | ARG269 |
| E | GLY270 |
| E | LEU272 |
| E | LYS756 |
| E | GLY788 |
| site_id | EC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 K 353 |
| Chain | Residue |
| K | SER129 |
| K | LYS200 |
| K | ARG204 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 G 993 |
| Chain | Residue |
| G | ARG670 |
| G | SER729 |
| G | ASN731 |
| G | GLY774 |
| site_id | EC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 G 994 |
| Chain | Residue |
| G | ALA608 |
| G | ARG670 |
| G | HIS864 |
| H | ARG739 |
| H | LYS832 |
| site_id | EC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 994 |
| Chain | Residue |
| C | ARG635 |
| D | LYS797 |
| D | SO4944 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 995 |
| Chain | Residue |
| C | ARG324 |
| C | PRO524 |
| C | ILE526 |
| C | PRO527 |
| C | SER528 |
| site_id | EC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 F 945 |
| Chain | Residue |
| E | ARG635 |
| F | GLN793 |
| F | GLY794 |
| F | LYS797 |
| site_id | FC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 E 994 |
| Chain | Residue |
| E | ARG324 |
| E | SER528 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 H 946 |
| Chain | Residue |
| G | ARG643 |
| G | HIS644 |
| H | ASN738 |
| H | ARG828 |
| site_id | FC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 999 |
| Chain | Residue |
| A | ARG396 |
| A | ARG487 |
| B | MET375 |
| B | HIS466 |
| B | ARG469 |
| site_id | FC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1000 |
| Chain | Residue |
| A | GLU401 |
| A | THR471 |
| A | SER472 |
| A | GLU473 |
| A | ARG490 |
| site_id | FC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | ARG451 |
| A | ARG618 |
| A | VAL655 |
| A | GLU656 |
| A | ASP657 |
| A | TRP658 |
| A | HIS659 |
| site_id | FC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | SER857 |
| A | ARG858 |
| A | THR859 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 996 |
| Chain | Residue |
| C | ARG396 |
| C | ARG487 |
| D | MET375 |
| D | HIS466 |
| D | ARG469 |
| site_id | FC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 997 |
| Chain | Residue |
| C | GLU401 |
| C | THR471 |
| C | SER472 |
| C | ARG490 |
| site_id | FC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 998 |
| Chain | Residue |
| C | ARG451 |
| C | ARG618 |
| C | VAL655 |
| C | GLU656 |
| C | ASP657 |
| C | TRP658 |
| C | HIS659 |
| site_id | GC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 999 |
| Chain | Residue |
| C | ARG858 |
| C | THR859 |
| D | HIS838 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 995 |
| Chain | Residue |
| E | ARG396 |
| E | ARG487 |
| F | MET375 |
| F | HIS466 |
| F | ARG469 |
| site_id | GC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 996 |
| Chain | Residue |
| E | GLU401 |
| E | THR471 |
| E | SER472 |
| E | GLU473 |
| E | ARG490 |
| site_id | GC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 E 997 |
| Chain | Residue |
| E | ARG451 |
| E | ARG618 |
| E | VAL655 |
| E | GLU656 |
| E | ASP657 |
| E | TRP658 |
| E | HIS659 |
| site_id | GC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 G 995 |
| Chain | Residue |
| G | ARG396 |
| G | ARG487 |
| H | MET375 |
| H | HIS466 |
| H | ARG469 |
| site_id | GC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 G 996 |
| Chain | Residue |
| G | GLU401 |
| G | THR471 |
| G | SER472 |
| G | ARG490 |
| site_id | GC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 G 997 |
| Chain | Residue |
| G | ARG451 |
| G | GLU656 |
| G | ASP657 |
| G | HIS659 |
| site_id | GC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 I 354 |
| Chain | Residue |
| I | SER6 |
| I | ARG9 |
| site_id | GC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 I 355 |
| Chain | Residue |
| I | ASN76 |
| I | ASN77 |
| site_id | HC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 I 356 |
| Chain | Residue |
| I | PRO181 |
| I | HIS196 |
| site_id | HC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 J 354 |
| Chain | Residue |
| J | SER6 |
| J | ARG9 |
| site_id | HC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 K 354 |
| Chain | Residue |
| K | ASN76 |
| K | ASN77 |
| site_id | HC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 L 352 |
| Chain | Residue |
| L | SER6 |
| L | ARG9 |
| site_id | HC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 L 353 |
| Chain | Residue |
| L | ASN76 |
| L | ASN77 |
| site_id | HC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 L 354 |
| Chain | Residue |
| L | PRO181 |
| L | HIS196 |
| L | TYR230 |
Functional Information from PROSITE/UniProt
| site_id | PS00433 |
| Number of Residues | 19 |
| Details | PHOSPHOFRUCTOKINASE Phosphofructokinase signature. RvttlGHvQRGGtavafDR |
| Chain | Residue | Details |
| B | ARG460-ARG478 | |
| B | LYS832-ARG850 | |
| A | ARG487-ARG505 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_03184 |
| Chain | Residue | Details |
| B | ASP333 | |
| D | ASP333 | |
| F | ASP333 | |
| H | ASP333 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 72 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03184 |
| Chain | Residue | Details |
| B | GLY191 | |
| B | HIS466 | |
| B | ARG643 | |
| B | THR701 | |
| B | ARG739 | |
| B | GLN746 | |
| B | GLU806 | |
| B | LYS832 | |
| B | HIS838 | |
| B | ARG918 | |
| D | GLY191 | |
| B | ARG255 | |
| D | ARG255 | |
| D | GLY285 | |
| D | ASP286 | |
| D | SER331 | |
| D | ARG368 | |
| D | MET375 | |
| D | GLU432 | |
| D | ARG460 | |
| D | HIS466 | |
| D | ARG643 | |
| B | GLY285 | |
| D | THR701 | |
| D | ARG739 | |
| D | GLN746 | |
| D | GLU806 | |
| D | LYS832 | |
| D | HIS838 | |
| D | ARG918 | |
| F | GLY191 | |
| F | ARG255 | |
| F | GLY285 | |
| B | ASP286 | |
| F | ASP286 | |
| F | SER331 | |
| F | ARG368 | |
| F | MET375 | |
| F | GLU432 | |
| F | ARG460 | |
| F | HIS466 | |
| F | ARG643 | |
| F | THR701 | |
| F | ARG739 | |
| B | SER331 | |
| F | GLN746 | |
| F | GLU806 | |
| F | LYS832 | |
| F | HIS838 | |
| F | ARG918 | |
| H | GLY191 | |
| H | ARG255 | |
| H | GLY285 | |
| H | ASP286 | |
| H | SER331 | |
| B | ARG368 | |
| H | ARG368 | |
| H | MET375 | |
| H | GLU432 | |
| H | ARG460 | |
| H | HIS466 | |
| H | ARG643 | |
| H | THR701 | |
| H | ARG739 | |
| H | GLN746 | |
| H | GLU806 | |
| B | MET375 | |
| H | LYS832 | |
| H | HIS838 | |
| H | ARG918 | |
| B | GLU432 | |
| B | ARG460 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20833871, ECO:0007744|PDB:3OPY |
| Chain | Residue | Details |
| B | ILE395 | |
| F | LYS400 | |
| F | GLN410 | |
| F | ASN557 | |
| H | ILE395 | |
| H | LYS400 | |
| H | GLN410 | |
| H | ASN557 | |
| B | LYS400 | |
| B | GLN410 | |
| B | ASN557 | |
| D | ILE395 | |
| D | LYS400 | |
| D | GLN410 | |
| D | ASN557 | |
| F | ILE395 |
