3OMF
Crystal structure of a histidine triad family protein from Entamoeba histolytica, bound to AMP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 114 |
| Chain | Residue |
| A | CYS5 |
| A | CYS8 |
| A | HIS47 |
| A | HIS97 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE AMP A 115 |
| Chain | Residue |
| A | ASN33 |
| A | LEU41 |
| A | ASN86 |
| A | GLY92 |
| A | GLN93 |
| A | THR94 |
| A | HIS99 |
| A | HIS101 |
| A | HOH150 |
| A | HOH199 |
| A | HOH205 |
| A | HOH223 |
| A | HOH262 |
| A | HOH271 |
| A | PHE29 |
| A | LYS30 |
| A | ASP31 |
| A | ILE32 |
| A | ILE32 |
Functional Information from PROSITE/UniProt
| site_id | PS00892 |
| Number of Residues | 19 |
| Details | HIT_1 HIT domain signature. NigedAgQtVkHIHFHILG |
| Chain | Residue | Details |
| A | ASN86-GLY104 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 107 |
| Details | Domain: {"description":"HIT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00464","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Histidine triad motif"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Tele-AMP-histidine intermediate","evidences":[{"source":"UniProtKB","id":"P49773","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3OJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OMF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OXK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25945711","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3OMF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
