3OLA
Poliovirus polymerase elongation complex with 2'-deoxy-CTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0039694 | biological_process | viral RNA genome replication |
| E | 0003723 | molecular_function | RNA binding |
| E | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| E | 0006351 | biological_process | DNA-templated transcription |
| E | 0039694 | biological_process | viral RNA genome replication |
| I | 0003723 | molecular_function | RNA binding |
| I | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| I | 0006351 | biological_process | DNA-templated transcription |
| I | 0039694 | biological_process | viral RNA genome replication |
| M | 0003723 | molecular_function | RNA binding |
| M | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| M | 0006351 | biological_process | DNA-templated transcription |
| M | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN M 2001 |
| Chain | Residue |
| M | HIS270 |
| M | HIS272 |
| M | CYS281 |
| M | HOH518 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN I 2002 |
| Chain | Residue |
| I | HIS270 |
| I | HIS272 |
| I | CYS281 |
| I | GOL8001 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN E 2003 |
| Chain | Residue |
| E | HIS272 |
| E | CYS281 |
| E | HIS270 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2004 |
| Chain | Residue |
| A | HIS270 |
| A | HIS272 |
| A | CYS281 |
| A | GOL8002 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DCP O 4001 |
| Chain | Residue |
| M | LYS159 |
| M | ARG174 |
| M | GLY236 |
| M | ASP238 |
| M | ASP328 |
| M | HOH505 |
| N | G600 |
| O | HOH296 |
| O | HOH493 |
| O | A701 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DCP K 4002 |
| Chain | Residue |
| I | ARG174 |
| I | GLY236 |
| I | ASP238 |
| I | ASN297 |
| I | ASP328 |
| I | HOH537 |
| J | G600 |
| K | HOH301 |
| K | HOH489 |
| K | A701 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA E 6007 |
| Chain | Residue |
| E | PRO202 |
| E | ASP213 |
| E | PHE217 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IPA E 6008 |
| Chain | Residue |
| E | ALA357 |
| E | SER360 |
| E | GLU364 |
| E | VAL366 |
| E | ASN370 |
| E | HOH568 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IPA E 6010 |
| Chain | Residue |
| E | GLU227 |
| E | LEU229 |
| E | VAL366 |
| E | THR367 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IPA A 6013 |
| Chain | Residue |
| A | PRO202 |
| A | CYS212 |
| A | ASP213 |
| A | PHE217 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA I 6014 |
| Chain | Residue |
| I | PRO202 |
| I | ASP213 |
| I | PHE217 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA M 6015 |
| Chain | Residue |
| M | GLU227 |
| M | LEU229 |
| M | VAL366 |
| M | THR367 |
| M | TRP368 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A 6016 |
| Chain | Residue |
| A | GLU227 |
| A | LEU229 |
| A | VAL366 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A 6017 |
| Chain | Residue |
| A | TYR313 |
| A | TYR334 |
| A | HIS336 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IPA M 6028 |
| Chain | Residue |
| M | ALA357 |
| M | SER360 |
| M | THR362 |
| M | GLU364 |
| M | VAL366 |
| M | ASN370 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA I 6029 |
| Chain | Residue |
| I | ALA122 |
| L | G806 |
| L | A807 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 7001 |
| Chain | Residue |
| A | ASP381 |
| A | GLU382 |
| A | LYS383 |
| A | HIS389 |
| A | TYR454 |
| site_id | BC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEG I 7002 |
| Chain | Residue |
| I | LEU162 |
| I | SER400 |
| I | TRP403 |
| I | THR404 |
| I | LYS405 |
| I | ASN409 |
| I | HIS413 |
| I | HOH547 |
| K | A697 |
| K | G698 |
| K | A699 |
| site_id | CC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PEG A 7003 |
| Chain | Residue |
| A | HOH515 |
| C | A697 |
| C | G698 |
| C | A699 |
| A | LEU25 |
| A | SER400 |
| A | TRP403 |
| A | THR404 |
| A | LYS405 |
| A | ASP406 |
| A | ASN409 |
| A | HIS413 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL I 8001 |
| Chain | Residue |
| I | TRP5 |
| I | HIS272 |
| I | ZN2002 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 8002 |
| Chain | Residue |
| A | TRP5 |
| A | HIS270 |
| A | HIS272 |
| A | LYS283 |
| A | ZN2004 |
