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3OL7

Poliovirus polymerase elongation complex with CTP

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0006351biological_processDNA-templated transcription
A0039694biological_processviral RNA genome replication
E0003723molecular_functionRNA binding
E0003968molecular_functionRNA-dependent RNA polymerase activity
E0006351biological_processDNA-templated transcription
E0039694biological_processviral RNA genome replication
I0003723molecular_functionRNA binding
I0003968molecular_functionRNA-dependent RNA polymerase activity
I0006351biological_processDNA-templated transcription
I0039694biological_processviral RNA genome replication
M0003723molecular_functionRNA binding
M0003968molecular_functionRNA-dependent RNA polymerase activity
M0006351biological_processDNA-templated transcription
M0039694biological_processviral RNA genome replication
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 3005
ChainResidue
AASP233
ATYR234
AASP328
APOP5004
CC702

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 3006
ChainResidue
CC702
AASP233
AASP328
AASP329
CA701

site_idAC3
Number of Residues9
DetailsBINDING SITE FOR RESIDUE POP A 5004
ChainResidue
AARG163
ALYS167
AARG174
AGLY236
ATYR237
AHOH585
AHOH588
AMG3005
CC702

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE IPA A 6009
ChainResidue
AGLY211
ACYS212
AASP213
APHE217
ALYS220

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE IPA A 6011
ChainResidue
ATYR313
AILE316
AHIS336

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE IPA A 6025
ChainResidue
AMET6
AGLU11

site_idAC7
Number of Residues9
DetailsBINDING SITE FOR RESIDUE PEG A 7001
ChainResidue
ASER28
AALA29
ATHR404
AASP406
AASN409
ATHR410
AHIS413
AHOH475
AHOH581

site_idAC8
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN A 2001
ChainResidue
AHIS270
AHIS272
ACYS281

site_idAC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG E 3002
ChainResidue
EASP233
EASP328
EASP329
GA701
GC702

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG E 3003
ChainResidue
EASP233
ETYR234
EASP328
EPOP5003
GC702

site_idBC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE POP E 5003
ChainResidue
EARG163
ELYS167
EARG174
ETYR234
EGLY236
ETYR237
EMG3003
GC702

site_idBC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE IPA E 6010
ChainResidue
ETYR313
EILE316
EHIS336
EHOH497

site_idBC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE IPA E 6013
ChainResidue
ETHR135
EASP137

site_idBC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE IPA E 6014
ChainResidue
ECYS212
EASP213
EPHE217
EHOH491

site_idBC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE IPA E 6015
ChainResidue
EGLY203
EVAL204
EILE205
ELEU224
EHOH490
EHOH528

site_idBC7
Number of Residues8
DetailsBINDING SITE FOR RESIDUE PEG E 7002
ChainResidue
ESER28
EALA29
ETHR404
EASP406
EASN409
ETHR410
EHIS413
GHOH45

site_idBC8
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL E 8008
ChainResidue
EMET6
EGLU11

site_idBC9
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN E 2002
ChainResidue
ETRP5
EHIS272
ECYS281

site_idCC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG I 3004
ChainResidue
IASP233
ITYR234
IASP328
KC702
KPOP5002

site_idCC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE IPA I 6012
ChainResidue
EGLU69
EASP71
IARG7

site_idCC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE IPA I 6023
ChainResidue
ELYS66
IARG7
IGLU11

site_idCC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE GOL I 8002
ChainResidue
IASN151
ILEU152
IPRO153
ILEU154
IHIS270
ISER271
IHIS272
IHOH613

site_idCC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL I 8003
ChainResidue
ILYS228
ILEU229
IGLU337
IVAL338
ITHR365
IVAL366
IGOL8004

site_idCC6
Number of Residues8
DetailsBINDING SITE FOR RESIDUE GOL I 8004
ChainResidue
IALA231
IASP339
IALA340
IPHE363
IGLU364
IVAL366
IHOH612
IGOL8003

site_idCC7
Number of Residues10
DetailsBINDING SITE FOR RESIDUE GOL I 8006
ChainResidue
ISER28
IALA29
IPHE30
ITHR404
IPRO407
ITHR410
IHIS413
IHOH523
IHOH541
IHOH614

site_idCC8
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN I 2003
ChainResidue
ITRP5
IHIS270
IHIS272
ICYS281
IHOH504

site_idCC9
Number of Residues2
DetailsBINDING SITE FOR RESIDUE PEG J 7003
ChainResidue
JU605
JC606

site_idDC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL J 8005
ChainResidue
ICYS212
ITYR326
JU603
JC604
KHOH211
KG700

site_idDC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE POP K 5002
ChainResidue
IARG163
IARG174
IGLY236
ITYR237
IMG3004
KHOH358
KC702

site_idDC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG M 3001
ChainResidue
MASP233
MTYR234
MASP328
MPOP5001
OC702

site_idDC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE POP M 5001
ChainResidue
MARG163
MLYS167
MARG174
MGLY236
MTYR237
MHOH562
MMG3001
OC702

site_idDC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE IPA M 6007
ChainResidue
AGLU69
AASP71

site_idDC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE IPA M 6016
ChainResidue
ALYS66
AILE67
MARG7
MGLU11

site_idDC7
Number of Residues3
DetailsBINDING SITE FOR RESIDUE IPA M 6019
ChainResidue
MTYR313
MTYR334
MHIS336

site_idDC8
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL M 8009
ChainResidue
MMET251
MGLU254
MLYS255

site_idDC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN M 2004
ChainResidue
MTRP5
MHIS270
MHIS272
MCYS281
MHOH523

site_idEC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE IPA N 6020
ChainResidue
NC606
NG607
NPEG7004

site_idEC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PEG N 7004
ChainResidue
NU605
NC606
NIPA6020

site_idEC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL N 8010
ChainResidue
MCYS212
MTYR326
MHOH557
NU603
NC604
OG700

site_idEC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE IPA O 6021
ChainResidue
OG693
OA694

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:21148772
ChainResidueDetails
AASP233
EASP233
IASP233
MASP233

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:21148772, ECO:0000305|PubMed:2196557
ChainResidueDetails
AASP328
EASP328
IASP328
MASP328

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PDB entries from 2024-11-13

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