Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001882 | molecular_function | nucleoside binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0006281 | biological_process | DNA repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE XJS A 1 |
| Chain | Residue |
| A | MG7 |
| A | ARG587 |
| A | ASP610 |
| A | TYR611 |
| A | SER612 |
| A | GLN613 |
| A | ILE614 |
| A | GLU615 |
| A | HIS639 |
| A | ARG659 |
| A | ARG660 |
| A | MG8 |
| A | LYS663 |
| A | PHE667 |
| A | ARG677 |
| A | ASP785 |
| A | HOH833 |
| B | HOH28 |
| B | DC111 |
| B | DOC112 |
| C | GOL8 |
| C | HOH33 |
| A | HOH33 |
| C | HOH42 |
| C | DA204 |
| C | DG205 |
| C | DG206 |
| A | HOH115 |
| A | HOH120 |
| A | HOH162 |
| A | HOH185 |
| A | HOH248 |
| A | ARG573 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | GOL6 |
| A | HOH37 |
| A | HOH55 |
| A | HOH100 |
| A | ASN485 |
| A | SER486 |
| A | ARG487 |
| A | ASP488 |
| C | DG211 |
| C | DT212 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 3 |
| Chain | Residue |
| A | HOH142 |
| A | HOH219 |
| A | HOH221 |
| A | HOH282 |
| A | ASP452 |
| A | TYR455 |
| A | ARG596 |
| A | ILE599 |
| A | ASP826 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 4 |
| Chain | Residue |
| A | HOH126 |
| A | HOH168 |
| A | THR544 |
| A | TYR545 |
| A | PRO579 |
| A | ASN580 |
| A | ASN583 |
| C | PGE6 |
| C | DC209 |
| C | DC210 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 5 |
| Chain | Residue |
| A | HOH53 |
| A | HOH176 |
| A | ARG313 |
| A | TRP318 |
| A | ASP551 |
| A | LEU552 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 6 |
| Chain | Residue |
| A | GOL2 |
| A | HOH37 |
| A | HOH67 |
| A | HOH125 |
| A | HOH223 |
| A | ASN485 |
| A | ARG487 |
| B | DG107 |
| B | DG108 |
| B | DC109 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 7 |
| Chain | Residue |
| A | XJS1 |
| A | MG8 |
| A | ASP610 |
| A | TYR611 |
| A | ASP785 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 8 |
| Chain | Residue |
| A | XJS1 |
| A | MG7 |
| A | HOH216 |
| A | ASP610 |
| A | ASP785 |
| A | HOH833 |
| B | DOC112 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 835 |
| Chain | Residue |
| A | HOH188 |
| A | HOH198 |
| A | GLU462 |
| A | GLU466 |
| A | ARG593 |
| A | GLU825 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 836 |
| Chain | Residue |
| A | ARG425 |
| A | PHE724 |
| A | HOH58 |
| A | HOH183 |
| A | HOH220 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 837 |
| Chain | Residue |
| A | HOH152 |
| A | GLU742 |
| A | GLU745 |
| A | ARG746 |
| C | DA203 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 838 |
| Chain | Residue |
| A | HOH155 |
| A | HOH166 |
| A | VAL310 |
| A | LEU311 |
| A | ARG405 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 840 |
| Chain | Residue |
| A | HOH150 |
| A | HOH235 |
| A | HOH235 |
| A | TYR455 |
| A | TYR455 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 841 |
| Chain | Residue |
| A | TRP417 |
| A | ARG431 |
| A | ARG435 |
| site_id | BC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL B 7 |
| Chain | Residue |
| B | HOH21 |
| B | HOH26 |
| B | HOH27 |
| B | HOH30 |
| B | DC106 |
| B | DG107 |
| B | DG108 |
| B | DC109 |
| C | HOH27 |
| C | HOH37 |
| C | DG208 |
| C | DC209 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE C 6 |
| Chain | Residue |
| A | GOL4 |
| A | HOH132 |
| A | ASP578 |
| C | DC209 |
| C | DC210 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 8 |
| Chain | Residue |
| A | XJS1 |
| C | HOH24 |
| C | DG205 |
| C | DG206 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 9 |
| Chain | Residue |
| A | ARG728 |
| C | DG206 |
| C | DC207 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RraAKtinFGvlYgmSahrL |
| Chain | Residue | Details |
| A | ARG659-LEU678 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 422 |
| Details | Region: {"description":"Polymerase","evidences":[{"evidenceCode":"ECO:0000250"}]} |
