3OBR
Crystal structure of Botulinum neurotoxin serotype D binding domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1 |
| Chain | Residue |
| A | HOH92 |
| A | HOH260 |
| A | GLU1114 |
| A | LYS1243 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | SER1241 |
| A | HOH238 |
| A | HOH293 |
| A | HOH496 |
| A | SER1115 |
| A | TRP1238 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 3 |
| Chain | Residue |
| A | HOH270 |
| A | HOH355 |
| A | PHE987 |
| A | TYR998 |
| A | ILE1019 |
| A | ASN1020 |
| A | GLU1022 |
| A | LYS1024 |
| A | LYS1213 |
| A | ASN1214 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 4 |
| Chain | Residue |
| A | HOH400 |
| A | ASN968 |
| A | ASN970 |
| A | ASP988 |
| A | SER990 |
| A | GLU991 |
| A | SER992 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 5 |
| Chain | Residue |
| A | LYS963 |
| A | GLN976 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 6 |
| Chain | Residue |
| A | HOH216 |
| A | THR1174 |
| A | TYR1176 |
| A | THR1178 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 7 |
| Chain | Residue |
| A | MET861 |
| A | ASN865 |
| A | LYS868 |
| A | VAL1075 |
| A | GLN1079 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 8 |
| Chain | Residue |
| A | HOH171 |
| A | HOH254 |
| A | HOH296 |
| A | HOH433 |
| A | TYR1076 |
| A | GLU1077 |
| A | ILE1080 |
| A | ARG1082 |
| A | VAL1211 |
| A | SER1212 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 9 |
| Chain | Residue |
| A | HOH310 |
| A | ASN1186 |
| A | CYS1187 |
| A | VAL1251 |
| A | THR1252 |
| A | ASN1253 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 10 |
| Chain | Residue |
| A | ASN898 |
| A | THR899 |
| A | ILE900 |
| A | THR902 |
| A | ARG1148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 219 |
| Details | Region: {"description":"N-terminus of receptor binding domain (N-RBD), Hcn","evidences":[{"source":"PubMed","id":"20704566","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20731382","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Region: {"description":"Ganglioside-binding loop","evidences":[{"source":"PubMed","id":"21632541","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Host ganglioside-binding motif","evidences":[{"source":"UniProtKB","id":"P0DPI0","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"20704566","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20704566","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3OBT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
