Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006565 | biological_process | L-serine catabolic process |
| A | 0008442 | molecular_function | 3-hydroxyisobutyrate dehydrogenase activity |
| A | 0009083 | biological_process | branched-chain amino acid catabolic process |
| A | 0016054 | biological_process | organic acid catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| A | 0051289 | biological_process | protein homotetramerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 402 |
| Chain | Residue |
| A | HIS11 |
| A | MSE12 |
| A | PHE239 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 403 |
| Chain | Residue |
| A | ASP38 |
| A | GLN242 |
| A | LEU276 |
| A | HOH551 |
| A | HOH555 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 404 |
| Chain | Residue |
| A | ARG233 |
| A | SER236 |
| A | GLY237 |
| A | GLY237 |
| A | GLY238 |
| A | ARG233 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 405 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE A 299 |
| Chain | Residue |
| A | VAL121 |
| A | GLY123 |
| A | GLY124 |
| A | LYS171 |
| A | ASN175 |
| A | TRP214 |
| A | TYR219 |
| A | PHE239 |
| A | ASP247 |
| A | HOH570 |
Functional Information from PROSITE/UniProt
| site_id | PS00895 |
| Number of Residues | 14 |
| Details | 3_HYDROXYISOBUT_DH 3-hydroxyisobutyrate dehydrogenase signature. FIGLGhMGapMAtN |
| Chain | Residue | Details |
| A | PHE6-ASN19 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS171 | |
| Chain | Residue | Details |
| A | LYS2 | |
| A | PRO66 | |
| A | THR96 | |
| A | LYS246 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | LEU65 | |
