3O8O
Structure of phosphofructokinase from Saccharomyces cerevisiae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003872 | molecular_function | 6-phosphofructokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| A | 0006096 | biological_process | glycolytic process |
| B | 0003872 | molecular_function | 6-phosphofructokinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| B | 0006096 | biological_process | glycolytic process |
| C | 0003872 | molecular_function | 6-phosphofructokinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| C | 0006096 | biological_process | glycolytic process |
| D | 0003872 | molecular_function | 6-phosphofructokinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| D | 0006096 | biological_process | glycolytic process |
| E | 0003872 | molecular_function | 6-phosphofructokinase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| E | 0006096 | biological_process | glycolytic process |
| F | 0003872 | molecular_function | 6-phosphofructokinase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| F | 0006096 | biological_process | glycolytic process |
| G | 0003872 | molecular_function | 6-phosphofructokinase activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| G | 0006096 | biological_process | glycolytic process |
| H | 0003872 | molecular_function | 6-phosphofructokinase activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006002 | biological_process | fructose 6-phosphate metabolic process |
| H | 0006096 | biological_process | glycolytic process |
Functional Information from PROSITE/UniProt
| site_id | PS00433 |
| Number of Residues | 19 |
| Details | PHOSPHOFRUCTOKINASE Phosphofructokinase signature. RittlGHvQRGGtavayDR |
| Chain | Residue | Details |
| B | ARG475-ARG493 | |
| B | LYS847-ARG865 | |
| A | LYS482-ARG500 | |
| A | ARG853-ARG871 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_03184 |
| Chain | Residue | Details |
| B | ASP348 | |
| D | ASP348 | |
| F | ASP348 | |
| H | ASP348 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03184 |
| Chain | Residue | Details |
| B | GLY206 | |
| D | ASP301 | |
| D | ARG754 | |
| D | LYS847 | |
| F | GLY206 | |
| F | ARG270 | |
| F | GLY300 | |
| F | ASP301 | |
| F | ARG754 | |
| F | LYS847 | |
| H | GLY206 | |
| B | ARG270 | |
| H | ARG270 | |
| H | GLY300 | |
| H | ASP301 | |
| H | ARG754 | |
| H | LYS847 | |
| B | GLY300 | |
| B | ASP301 | |
| B | ARG754 | |
| B | LYS847 | |
| D | GLY206 | |
| D | ARG270 | |
| D | GLY300 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 44 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03184, ECO:0000269|PubMed:21241708 |
| Chain | Residue | Details |
| B | SER346 | |
| B | HIS853 | |
| B | ARG935 | |
| D | SER346 | |
| D | ARG383 | |
| D | MET390 | |
| D | GLU447 | |
| D | ARG475 | |
| D | HIS481 | |
| D | ARG658 | |
| D | THR716 | |
| B | ARG383 | |
| D | GLN761 | |
| D | HIS853 | |
| D | ARG935 | |
| F | SER346 | |
| F | ARG383 | |
| F | MET390 | |
| F | GLU447 | |
| F | ARG475 | |
| F | HIS481 | |
| F | ARG658 | |
| B | MET390 | |
| F | THR716 | |
| F | GLN761 | |
| F | HIS853 | |
| F | ARG935 | |
| H | SER346 | |
| H | ARG383 | |
| H | MET390 | |
| H | GLU447 | |
| H | ARG475 | |
| H | HIS481 | |
| B | GLU447 | |
| H | ARG658 | |
| H | THR716 | |
| H | GLN761 | |
| H | HIS853 | |
| H | ARG935 | |
| B | ARG475 | |
| B | HIS481 | |
| B | ARG658 | |
| B | THR716 | |
| B | GLN761 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956 |
| Chain | Residue | Details |
| B | SER803 | |
| G | ARG391 | |
| G | GLU455 | |
| G | LYS482 | |
| D | SER803 | |
| F | SER803 | |
| H | SER803 | |
| C | GLU455 | |
| C | LYS482 | |
| E | ARG391 | |
| E | GLU455 | |
| E | LYS482 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | SER217 | |
| C | SER217 | |
| E | SER217 | |
| G | SER217 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | THR450 | |
| C | THR450 | |
| E | THR450 | |
| G | THR450 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| A | LYS625 | |
| C | LYS625 | |
| E | LYS625 | |
| G | LYS625 |
