3O7Q
Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0015150 | molecular_function | fucose transmembrane transporter activity |
| A | 0015293 | molecular_function | symporter activity |
| A | 0015517 | molecular_function | galactose:proton symporter activity |
| A | 0015518 | molecular_function | arabinose:proton symporter activity |
| A | 0015535 | molecular_function | fucose:proton symporter activity |
| A | 0015751 | biological_process | arabinose transmembrane transport |
| A | 0015756 | biological_process | fucose transmembrane transport |
| A | 0015757 | biological_process | galactose transmembrane transport |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0071702 | biological_process | organic substance transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 70 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:20877283 |
| Chain | Residue | Details |
| A | GLY2-ILE26 | |
| A | LEU88-TYR90 | |
| A | LEU145-SER150 | |
| A | LEU228-ILE257 | |
| A | SER320-PRO324 | |
| A | ILE373-ASP379 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 301 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:20877283 |
| Chain | Residue | Details |
| A | PRO27-GLN53 | |
| A | GLN62-LYS87 | |
| A | LYS91-GLU113 | |
| A | THR118-VAL144 | |
| A | GLY151-LEU178 | |
| A | PRO194-MET227 | |
| A | ARG258-GLU287 | |
| A | ALA294-ILE319 | |
| A | HIS325-ALA343 | |
| A | HIS348-GLY372 | |
| A | THR380-ALA407 | |
| A | ILE411-ARG430 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:20877283 |
| Chain | Residue | Details |
| A | GLN54-PHE61 | |
| A | ILE114-TYR117 | |
| A | SER179-SER193 | |
| A | GLU288-THR293 | |
| A | PHE344-GLY347 | |
| A | ALA408-ASN410 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:20877283 |
| Chain | Residue | Details |
| A | PHE431-ASN438 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Important for activity => ECO:0000269|PubMed:20877283 |
| Chain | Residue | Details |
| A | ASP46 | |
| A | GLU135 |
