Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004766 | molecular_function | spermidine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0008295 | biological_process | spermidine biosynthetic process |
| A | 0010487 | molecular_function | thermospermine synthase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016768 | molecular_function | spermine synthase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004766 | molecular_function | spermidine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0008295 | biological_process | spermidine biosynthetic process |
| B | 0010487 | molecular_function | thermospermine synthase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016768 | molecular_function | spermine synthase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004766 | molecular_function | spermidine synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006596 | biological_process | polyamine biosynthetic process |
| C | 0008295 | biological_process | spermidine biosynthetic process |
| C | 0010487 | molecular_function | thermospermine synthase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016768 | molecular_function | spermine synthase activity |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004766 | molecular_function | spermidine synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006596 | biological_process | polyamine biosynthetic process |
| D | 0008295 | biological_process | spermidine biosynthetic process |
| D | 0010487 | molecular_function | thermospermine synthase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016768 | molecular_function | spermine synthase activity |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004766 | molecular_function | spermidine synthase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006596 | biological_process | polyamine biosynthetic process |
| E | 0008295 | biological_process | spermidine biosynthetic process |
| E | 0010487 | molecular_function | thermospermine synthase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016768 | molecular_function | spermine synthase activity |
| E | 0042803 | molecular_function | protein homodimerization activity |
| E | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004766 | molecular_function | spermidine synthase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006596 | biological_process | polyamine biosynthetic process |
| F | 0008295 | biological_process | spermidine biosynthetic process |
| F | 0010487 | molecular_function | thermospermine synthase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016768 | molecular_function | spermine synthase activity |
| F | 0042803 | molecular_function | protein homodimerization activity |
| F | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0004766 | molecular_function | spermidine synthase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005829 | cellular_component | cytosol |
| G | 0006596 | biological_process | polyamine biosynthetic process |
| G | 0008295 | biological_process | spermidine biosynthetic process |
| G | 0010487 | molecular_function | thermospermine synthase activity |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016768 | molecular_function | spermine synthase activity |
| G | 0042803 | molecular_function | protein homodimerization activity |
| G | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0004766 | molecular_function | spermidine synthase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005829 | cellular_component | cytosol |
| H | 0006596 | biological_process | polyamine biosynthetic process |
| H | 0008295 | biological_process | spermidine biosynthetic process |
| H | 0010487 | molecular_function | thermospermine synthase activity |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016768 | molecular_function | spermine synthase activity |
| H | 0042803 | molecular_function | protein homodimerization activity |
| H | 0043918 | molecular_function | cadaverine aminopropyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 289 |
| Chain | Residue |
| A | ARG243 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 290 |
| Chain | Residue |
| A | ARG97 |
| A | ARG262 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 291 |
| Chain | Residue |
| A | ASN265 |
| A | PRO266 |
| A | ALA267 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 292 |
| Chain | Residue |
| E | SER168 |
| E | LEU169 |
| E | PHE170 |
| E | THR171 |
| A | HIS12 |
| A | ASP13 |
| A | GLN14 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 289 |
| Chain | Residue |
| B | ARG97 |
| B | ARG262 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 289 |
| Chain | Residue |
| C | ARG243 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 290 |
| Chain | Residue |
| C | ARG97 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 291 |
| Chain | Residue |
| C | SER168 |
| C | LEU169 |
| C | PHE170 |
| C | THR171 |
| G | HIS12 |
| G | ASP13 |
| G | GLN14 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 292 |
| Chain | Residue |
| B | THR171 |
| C | LYS135 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 293 |
| Chain | Residue |
| C | GLN191 |
| C | TYR226 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 294 |
| Chain | Residue |
| C | HIS12 |
| C | ASP13 |
| C | GLN14 |
| G | SER168 |
| G | LEU169 |
| G | PHE170 |
| G | THR171 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 D 289 |
| Chain | Residue |
| D | ARG243 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 290 |
| Chain | Residue |
| D | ARG97 |
| D | ARG262 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 291 |
| Chain | Residue |
| D | ASN23 |
| D | VAL24 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 D 292 |
| Chain | Residue |
| D | GLN147 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 E 289 |
| Chain | Residue |
| E | ARG243 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 E 290 |
| Chain | Residue |
| A | SER168 |
| A | LEU169 |
| A | PHE170 |
| A | THR171 |
| E | HIS12 |
| E | ASP13 |
| E | GLN14 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 E 291 |
| Chain | Residue |
| E | ARG97 |
| E | ARG262 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 292 |
| Chain | Residue |
| E | PRO184 |
| E | ASP238 |
| E | ASN239 |
| site_id | CC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 F 289 |
| Chain | Residue |
| F | ARG243 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 F 290 |
| Chain | Residue |
| F | ARG262 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 F 291 |
| Chain | Residue |
| F | ARG207 |
| site_id | CC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 F 292 |
| Chain | Residue |
| F | GLN191 |
| site_id | CC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 G 289 |
| Chain | Residue |
| G | ARG243 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 G 290 |
| Chain | Residue |
| G | LEU11 |
| G | GLY193 |
| G | VAL194 |
| G | SO4291 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 G 291 |
| Chain | Residue |
| G | VAL53 |
| G | TYR226 |
| G | SO4290 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 G 292 |
| Chain | Residue |
| G | PRO184 |
| G | GLY185 |
| G | ASP238 |
| G | ASN239 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 G 293 |
| Chain | Residue |
| G | ARG97 |
| G | ARG262 |
| site_id | DC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 H 289 |
| Chain | Residue |
| H | ARG97 |
| H | ARG262 |
| site_id | DC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 H 290 |
| Chain | Residue |
| H | ARG243 |
Functional Information from PROSITE/UniProt
| site_id | PS01330 |
| Number of Residues | 14 |
| Details | PABS_1 Polyamine biosynthesis (PABS) domain signature. VLIIGGGdGamLrE |
| Chain | Residue | Details |
| A | VAL81-GLU94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23001854","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 62 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 458 |
| Details | Domain: {"description":"PABS","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
