3O2P

A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB)

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0031461	cellular_component	cullin-RING ubiquitin ligase complex
E	0031625	molecular_function	ubiquitin protein ligase binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 3968

Chain	Residue
A	HOH8
E	LYS799
A	ASP153
A	HIS157
A	GOL270
A	HOH282
E	HOH40
E	GLU752
E	ALA753
E	LEU796

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 270

Chain	Residue
A	HOH2
A	ASP106
A	LEU107
A	ALA108
A	ASP153
A	TYR199
A	GOL3968
E	LYS799

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL E 3968

Chain	Residue
A	ALA253
A	TRP254
A	PRO255
A	PHE256
E	HIS767
E	LYS790
E	ILE793
E	ASP794
E	ARG804
E	TYR811

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Functional Information from PROSITE/UniProt

site_id	PS01256
Number of Residues	27
Details	CULLIN_1 Cullin family signature. VKraIdsLIQKgYLqRgddges.YaYlA

Chain	Residue	Details
E	VAL789-ALA815

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	61
Details	Domain: {"description":"Cullin neddylation","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in NEDD8)","evidences":[{"source":"UniProtKB","id":"Q13616","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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