Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE O28 A 264 |
| Chain | Residue |
| A | ILE92 |
| A | GLY219 |
| A | GLY219 |
| A | LEU239 |
| A | SER242 |
| A | LYS104 |
| A | PRO105 |
| A | PRO105 |
| A | SER108 |
| A | SER108 |
| A | SER217 |
| A | LYS218 |
| A | LYS218 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 265 |
| Chain | Residue |
| A | TYR61 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | LEU138 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| A | HOH278 |
| A | HOH284 |
| A | HOH300 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 266 |
| Chain | Residue |
| A | GLU24 |
| A | ARG31 |
| A | HIS46 |
| A | LYS240 |
| A | GLN244 |
| A | SO4268 |
| A | HOH319 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 267 |
| Chain | Residue |
| A | SER140 |
| A | LYS144 |
| A | ARG148 |
| A | HOH341 |
| A | HOH373 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 268 |
| Chain | Residue |
| A | HIS23 |
| A | GLU24 |
| A | ARG31 |
| A | LYS240 |
| A | SO4266 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS A 269 |
| Chain | Residue |
| A | GLU27 |
| A | ASN29 |
| A | GLU30 |
| A | ARG149 |
| A | LYS151 |
| A | HOH412 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 270 |
| Chain | Residue |
| A | GLY62 |
| A | ALA63 |
| A | TRP71 |
| A | THR93 |
| A | VAL95 |
| A | ARG96 |
| A | GLU145 |
| A | HOH312 |
| A | HOH330 |
| A | HOH373 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 271 |
| Chain | Residue |
| A | GLU97 |
| A | ASP101 |
| A | PHE102 |
| A | LYS104 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 272 |
| Chain | Residue |
| A | TRP159 |
| A | ARG163 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 273 |
| Chain | Residue |
| A | GLU27 |
| A | ARG149 |
| A | LYS151 |
| A | GLU243 |
| A | GLN244 |
| A | HOH310 |
| A | HOH367 |
| A | HOH417 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 274 |
| Chain | Residue |
| A | SER194 |
| A | GLU198 |
| A | ASN214 |
| A | HOH344 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 275 |
| Chain | Residue |
| A | ASN214 |
| A | ASP216 |
| A | SER217 |
| A | ASP248 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO89 | |
| A | THR91 | |
| A | ARG96 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
