3NZK
Structure of LpxC from Yersinia enterocolitica Complexed with CHIR090 Inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0008759 | molecular_function | obsolete UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019637 | biological_process | organophosphate metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0103117 | molecular_function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity |
| A | 1901135 | biological_process | carbohydrate derivative metabolic process |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0008759 | molecular_function | obsolete UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity |
| B | 0009245 | biological_process | lipid A biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019637 | biological_process | organophosphate metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0103117 | molecular_function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity |
| B | 1901135 | biological_process | carbohydrate derivative metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE C90 A 501 |
| Chain | Residue |
| A | GLU78 |
| A | SER211 |
| A | VAL217 |
| A | HIS238 |
| A | ASP242 |
| A | HIS265 |
| A | ZN307 |
| A | HOH366 |
| A | HOH390 |
| A | HOH400 |
| A | HOH454 |
| A | HIS79 |
| A | THR191 |
| A | PHE192 |
| A | MET195 |
| A | ILE198 |
| A | GLN202 |
| A | CYS207 |
| A | GLY210 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 307 |
| Chain | Residue |
| A | HIS79 |
| A | HIS238 |
| A | ASP242 |
| A | C90501 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 3968 |
| Chain | Residue |
| A | GLU134 |
| A | GLU280 |
| A | HOH451 |
| B | GLU69 |
| B | ASP220 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C90 B 501 |
| Chain | Residue |
| B | GLU78 |
| B | HIS79 |
| B | THR191 |
| B | PHE192 |
| B | ILE198 |
| B | GLN202 |
| B | CYS207 |
| B | GLY210 |
| B | SER211 |
| B | PHE212 |
| B | VAL217 |
| B | HIS238 |
| B | ASP242 |
| B | HIS265 |
| B | ZN307 |
| B | HOH363 |
| B | HOH373 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 307 |
| Chain | Residue |
| B | HIS79 |
| B | HIS238 |
| B | ASP242 |
| B | C90501 |
