3NV8
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol pyruvate and manganese (thesit-free)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005829 | cellular_component | cytosol |
A | 0005886 | cellular_component | plasma membrane |
A | 0008652 | biological_process | amino acid biosynthetic process |
A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
A | 0009274 | cellular_component | peptidoglycan-based cell wall |
A | 0009423 | biological_process | chorismate biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0030145 | molecular_function | manganese ion binding |
A | 0046872 | molecular_function | metal ion binding |
A | 0051260 | biological_process | protein homooligomerization |
B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005829 | cellular_component | cytosol |
B | 0005886 | cellular_component | plasma membrane |
B | 0008652 | biological_process | amino acid biosynthetic process |
B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
B | 0009274 | cellular_component | peptidoglycan-based cell wall |
B | 0009423 | biological_process | chorismate biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0030145 | molecular_function | manganese ion binding |
B | 0046872 | molecular_function | metal ion binding |
B | 0051260 | biological_process | protein homooligomerization |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 463 |
Chain | Residue |
A | ASP138 |
A | ARG145 |
A | ARG148 |
A | HIS164 |
A | HOH549 |
A | HOH597 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MN A 464 |
Chain | Residue |
A | ASP441 |
A | CYS87 |
A | HIS369 |
A | GLU411 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 465 |
Chain | Residue |
A | ARG168 |
A | ARG171 |
B | PRO8 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 466 |
Chain | Residue |
A | ARG171 |
A | ALA174 |
A | ASN175 |
B | ILE7 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PEP A 467 |
Chain | Residue |
A | ARG126 |
A | GLU248 |
A | TRP280 |
A | GLY282 |
A | GLU283 |
A | LYS306 |
A | ARG337 |
A | HIS369 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 463 |
Chain | Residue |
B | ARG23 |
B | LEU26 |
B | ARG49 |
B | ARG256 |
B | HOH502 |
B | HOH600 |
site_id | AC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 B 464 |
Chain | Residue |
B | ARG135 |
B | SER136 |
B | ALA137 |
B | ARG284 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MN B 465 |
Chain | Residue |
B | CYS87 |
B | HIS369 |
B | GLU411 |
B | ASP441 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL B 466 |
Chain | Residue |
B | THR114 |
B | VAL121 |
B | LYS123 |
B | LEU194 |
site_id | BC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL B 467 |
Chain | Residue |
B | GLN70 |
B | VAL121 |
B | VAL122 |
B | LYS123 |
B | GLU242 |
B | HOH516 |
B | HOH573 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL B 468 |
Chain | Residue |
B | PRO17 |
B | LEU18 |
B | ARG23 |
B | LEU144 |
B | ALA159 |
site_id | BC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL B 469 |
Chain | Residue |
B | ARG25 |
B | ALA294 |
B | GLN297 |
B | VAL298 |
B | HOH610 |
B | HOH613 |
site_id | BC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 470 |
Chain | Residue |
B | ARG49 |
B | HOH504 |
B | HOH612 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PO4 B 471 |
Chain | Residue |
B | GLY282 |
B | GLU283 |
B | LYS306 |
B | ARG337 |
B | HIS369 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 16 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16288916, ECO:0007744|PDB:2B7O |
Chain | Residue | Details |
A | CYS87 | |
B | ARG126 | |
B | GLU283 | |
B | LYS306 | |
B | ARG337 | |
B | HIS369 | |
B | GLU411 | |
B | ASP441 | |
A | ARG126 | |
A | GLU283 | |
A | LYS306 | |
A | ARG337 | |
A | HIS369 | |
A | GLU411 | |
A | ASP441 | |
B | CYS87 |