Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3NQ4

30mer structure of Lumazine synthase from Salmonella typhimurium LT2

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
1	0005829	cellular_component	cytosol
1	0009231	biological_process	riboflavin biosynthetic process
1	0009349	cellular_component	riboflavin synthase complex
1	0016740	molecular_function	transferase activity
2	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
2	0005829	cellular_component	cytosol
2	0009231	biological_process	riboflavin biosynthetic process
2	0009349	cellular_component	riboflavin synthase complex
2	0016740	molecular_function	transferase activity
3	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
3	0005829	cellular_component	cytosol
3	0009231	biological_process	riboflavin biosynthetic process
3	0009349	cellular_component	riboflavin synthase complex
3	0016740	molecular_function	transferase activity
4	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
4	0005829	cellular_component	cytosol
4	0009231	biological_process	riboflavin biosynthetic process
4	0009349	cellular_component	riboflavin synthase complex
4	0016740	molecular_function	transferase activity
A	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
A	0005829	cellular_component	cytosol
A	0009231	biological_process	riboflavin biosynthetic process
A	0009349	cellular_component	riboflavin synthase complex
A	0016740	molecular_function	transferase activity
B	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
B	0005829	cellular_component	cytosol
B	0009231	biological_process	riboflavin biosynthetic process
B	0009349	cellular_component	riboflavin synthase complex
B	0016740	molecular_function	transferase activity
C	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
C	0005829	cellular_component	cytosol
C	0009231	biological_process	riboflavin biosynthetic process
C	0009349	cellular_component	riboflavin synthase complex
C	0016740	molecular_function	transferase activity
D	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
D	0005829	cellular_component	cytosol
D	0009231	biological_process	riboflavin biosynthetic process
D	0009349	cellular_component	riboflavin synthase complex
D	0016740	molecular_function	transferase activity
E	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
E	0005829	cellular_component	cytosol
E	0009231	biological_process	riboflavin biosynthetic process
E	0009349	cellular_component	riboflavin synthase complex
E	0016740	molecular_function	transferase activity
F	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
F	0005829	cellular_component	cytosol
F	0009231	biological_process	riboflavin biosynthetic process
F	0009349	cellular_component	riboflavin synthase complex
F	0016740	molecular_function	transferase activity
G	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
G	0005829	cellular_component	cytosol
G	0009231	biological_process	riboflavin biosynthetic process
G	0009349	cellular_component	riboflavin synthase complex
G	0016740	molecular_function	transferase activity
H	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
H	0005829	cellular_component	cytosol
H	0009231	biological_process	riboflavin biosynthetic process
H	0009349	cellular_component	riboflavin synthase complex
H	0016740	molecular_function	transferase activity
I	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
I	0005829	cellular_component	cytosol
I	0009231	biological_process	riboflavin biosynthetic process
I	0009349	cellular_component	riboflavin synthase complex
I	0016740	molecular_function	transferase activity
J	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
J	0005829	cellular_component	cytosol
J	0009231	biological_process	riboflavin biosynthetic process
J	0009349	cellular_component	riboflavin synthase complex
J	0016740	molecular_function	transferase activity
K	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
K	0005829	cellular_component	cytosol
K	0009231	biological_process	riboflavin biosynthetic process
K	0009349	cellular_component	riboflavin synthase complex
K	0016740	molecular_function	transferase activity
L	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
L	0005829	cellular_component	cytosol
L	0009231	biological_process	riboflavin biosynthetic process
L	0009349	cellular_component	riboflavin synthase complex
L	0016740	molecular_function	transferase activity
M	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
M	0005829	cellular_component	cytosol
M	0009231	biological_process	riboflavin biosynthetic process
M	0009349	cellular_component	riboflavin synthase complex
M	0016740	molecular_function	transferase activity
N	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
N	0005829	cellular_component	cytosol
N	0009231	biological_process	riboflavin biosynthetic process
N	0009349	cellular_component	riboflavin synthase complex
N	0016740	molecular_function	transferase activity
O	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
O	0005829	cellular_component	cytosol
O	0009231	biological_process	riboflavin biosynthetic process
O	0009349	cellular_component	riboflavin synthase complex
O	0016740	molecular_function	transferase activity
P	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
P	0005829	cellular_component	cytosol
P	0009231	biological_process	riboflavin biosynthetic process
P	0009349	cellular_component	riboflavin synthase complex
P	0016740	molecular_function	transferase activity
Q	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
Q	0005829	cellular_component	cytosol
Q	0009231	biological_process	riboflavin biosynthetic process
Q	0009349	cellular_component	riboflavin synthase complex
Q	0016740	molecular_function	transferase activity
R	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
R	0005829	cellular_component	cytosol
R	0009231	biological_process	riboflavin biosynthetic process
R	0009349	cellular_component	riboflavin synthase complex
R	0016740	molecular_function	transferase activity
S	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
S	0005829	cellular_component	cytosol
S	0009231	biological_process	riboflavin biosynthetic process
S	0009349	cellular_component	riboflavin synthase complex
S	0016740	molecular_function	transferase activity
T	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
T	0005829	cellular_component	cytosol
T	0009231	biological_process	riboflavin biosynthetic process
T	0009349	cellular_component	riboflavin synthase complex
T	0016740	molecular_function	transferase activity
U	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
U	0005829	cellular_component	cytosol
U	0009231	biological_process	riboflavin biosynthetic process
U	0009349	cellular_component	riboflavin synthase complex
U	0016740	molecular_function	transferase activity
V	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
V	0005829	cellular_component	cytosol
V	0009231	biological_process	riboflavin biosynthetic process
V	0009349	cellular_component	riboflavin synthase complex
V	0016740	molecular_function	transferase activity
W	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
W	0005829	cellular_component	cytosol
W	0009231	biological_process	riboflavin biosynthetic process
W	0009349	cellular_component	riboflavin synthase complex
W	0016740	molecular_function	transferase activity
X	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
X	0005829	cellular_component	cytosol
X	0009231	biological_process	riboflavin biosynthetic process
X	0009349	cellular_component	riboflavin synthase complex
X	0016740	molecular_function	transferase activity
Y	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
Y	0005829	cellular_component	cytosol
Y	0009231	biological_process	riboflavin biosynthetic process
Y	0009349	cellular_component	riboflavin synthase complex
Y	0016740	molecular_function	transferase activity
Z	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
Z	0005829	cellular_component	cytosol
Z	0009231	biological_process	riboflavin biosynthetic process
Z	0009349	cellular_component	riboflavin synthase complex
Z	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 157

Chain	Residue
A	GLY85
A	GLY86
A	THR87
E	ARG128

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 157

Chain	Residue
A	ARG128
B	GLY85
B	GLY86
B	THR87
B	HIS89

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 158

Chain	Residue
B	ARG128
C	GLY85
C	GLY86

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 157

Chain	Residue
C	GLY85
C	GLY86
C	THR87

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 157

Chain	Residue
C	ARG128
D	GLY86
D	THR87
D	HIS89

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 158

Chain	Residue
D	GLU127
D	LYS132

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 157

Chain	Residue
D	ARG128
E	GLY86
E	THR87
E	HIS89

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 158

Chain	Residue
F	GLN124
F	GLU127
F	ARG128
G	GLY86

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 G 157

Chain	Residue
G	GLY85
G	THR87
G	HIS89

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 157

Chain	Residue
G	ARG128
H	GLY85
H	GLY86
H	THR87
H	HIS89

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 158

Chain	Residue
H	GLU123
H	GLN124
H	GLU127

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 159

Chain	Residue
H	ARG128
I	GLY85
I	GLY86
I	THR87

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 157

Chain	Residue
F	GLY86
F	THR87
J	ARG128

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 J 158

Chain	Residue
J	THR87
J	HIS89

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 K 157

Chain	Residue
K	GLY85
K	GLY86
K	THR87
O	ARG128

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 157

Chain	Residue
K	ARG128
L	GLY85
L	GLY86
L	THR87
L	HIS89

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 L 158

Chain	Residue
L	GLU127

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 M 157

Chain	Residue
L	ARG128
M	GLY85
M	GLY86
M	THR87

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 M 158

Chain	Residue
M	GLU127

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 M 159

Chain	Residue
M	ARG128
N	GLY85
N	GLY86
N	THR87

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 N 157

Chain	Residue
N	ARG128
O	GLY86
O	THR87

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 P 157

Chain	Residue
P	GLY85
P	GLY86
P	THR87
T	ARG128

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 Q 157

Chain	Residue
P	ARG128
Q	GLY85
Q	GLY86
Q	THR87
Q	HIS89

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 Q 158

Chain	Residue
Q	GLU127
Q	ARG128

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 Q 159

Chain	Residue
Q	ARG128
R	THR87
R	HIS89

site_id	CC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 R 158

Chain	Residue
R	ARG128
S	GLY85
S	GLY86
S	THR87
S	HIS89

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 S 157

Chain	Residue
S	ARG128
T	GLY85
T	GLY86

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 U 157

Chain	Residue
U	THR87
U	HIS89
Y	ARG128

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 V 157

Chain	Residue
V	THR87
V	HIS89
U	ARG128
V	GLY85
V	GLY86

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 V 158

Chain	Residue
V	ARG128
W	GLY85
W	THR87

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 X 157

Chain	Residue
X	ARG128
Y	GLY86
Y	THR87
Y	HIS89

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 X 158

Chain	Residue
W	ARG128
X	GLY85
X	GLY86
X	THR87
X	HIS89

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 Z 157

Chain	Residue
Z	ILE83
Z	THR87
Z	HIS89

site_id	DC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 Z 158

Chain	Residue
1	GLY86
1	SO4157
Z	GLU127
Z	ARG128

site_id	DC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 1 157

Chain	Residue
1	GLY85
1	GLY86
1	THR87
Z	ARG128
Z	SO4158

site_id	DC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 1 158

Chain	Residue
1	GLN124
1	GLU127
1	ARG128
2	GLY86

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 2 157

Chain	Residue
1	ARG128
2	GLY85
2	GLY86
2	THR87

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 2 158

Chain	Residue
2	GLU127
2	ARG128
2	SO4159
3	GLY86

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 2 159

Chain	Residue
2	ARG128
2	SO4158
3	GLY86
3	THR87

site_id	EC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 3 157

Chain	Residue
3	ARG128
4	GLY85
4	GLY86
4	THR87
4	HIS89

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	ACT_SITE: Proton donor => ECO:0000255

Chain	Residue	Details
A	HIS89
J	HIS89
K	HIS89
L	HIS89
M	HIS89
N	HIS89
O	HIS89
P	HIS89
Q	HIS89
R	HIS89
S	HIS89
B	HIS89
T	HIS89
U	HIS89
V	HIS89
W	HIS89
X	HIS89
Y	HIS89
Z	HIS89
1	HIS89
2	HIS89
3	HIS89
C	HIS89
4	HIS89
D	HIS89
E	HIS89
F	HIS89
G	HIS89
H	HIS89
I	HIS89

site_id	SWS_FT_FI2
Number of Residues	120
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	PHE22
C	ALA57
Y	PHE114
Z	PHE22
Z	ALA57
Z	THR81
Z	PHE114
1	PHE22
1	ALA57
1	THR81
1	PHE114
2	PHE22
C	THR81
2	ALA57
2	THR81
2	PHE114
3	PHE22
3	ALA57
3	THR81
3	PHE114
4	PHE22
4	ALA57
4	THR81
C	PHE114
4	PHE114
D	PHE22
D	ALA57
D	THR81
D	PHE114
E	PHE22
E	ALA57
E	THR81
A	ALA57
E	PHE114
F	PHE22
F	ALA57
F	THR81
F	PHE114
G	PHE22
G	ALA57
G	THR81
G	PHE114
H	PHE22
A	THR81
H	ALA57
H	THR81
H	PHE114
I	PHE22
I	ALA57
I	THR81
I	PHE114
J	PHE22
J	ALA57
J	THR81
A	PHE114
J	PHE114
K	PHE22
K	ALA57
K	THR81
K	PHE114
L	PHE22
L	ALA57
L	THR81
L	PHE114
M	PHE22
B	PHE22
M	ALA57
M	THR81
M	PHE114
N	PHE22
N	ALA57
N	THR81
N	PHE114
O	PHE22
O	ALA57
O	THR81
B	ALA57
O	PHE114
P	PHE22
P	ALA57
P	THR81
P	PHE114
Q	PHE22
Q	ALA57
Q	THR81
Q	PHE114
R	PHE22
B	THR81
R	ALA57
R	THR81
R	PHE114
S	PHE22
S	ALA57
S	THR81
S	PHE114
T	PHE22
T	ALA57
T	THR81
B	PHE114
T	PHE114
U	PHE22
U	ALA57
U	THR81
U	PHE114
V	PHE22
V	ALA57
V	THR81
V	PHE114
W	PHE22
C	PHE22
W	ALA57
W	THR81
W	PHE114
X	PHE22
X	ALA57
X	THR81
X	PHE114
Y	PHE22
Y	ALA57
Y	THR81

site_id	SWS_FT_FI3
Number of Residues	60
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	GLY86
E	ARG128
F	GLY86
F	ARG128
G	GLY86
G	ARG128
H	GLY86
H	ARG128
I	GLY86
I	ARG128
J	GLY86
A	ARG128
J	ARG128
K	GLY86
K	ARG128
L	GLY86
L	ARG128
M	GLY86
M	ARG128
N	GLY86
N	ARG128
O	GLY86
B	GLY86
O	ARG128
P	GLY86
P	ARG128
Q	GLY86
Q	ARG128
R	GLY86
R	ARG128
S	GLY86
S	ARG128
T	GLY86
B	ARG128
T	ARG128
U	GLY86
U	ARG128
V	GLY86
V	ARG128
W	GLY86
W	ARG128
X	GLY86
X	ARG128
Y	GLY86
C	GLY86
Y	ARG128
Z	GLY86
Z	ARG128
1	GLY86
1	ARG128
2	GLY86
2	ARG128
3	GLY86
3	ARG128
4	GLY86
C	ARG128
4	ARG128
D	GLY86
D	ARG128
E	GLY86

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)