3NIC

DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009036	molecular_function	type II site-specific deoxyribonuclease activity
A	0042802	molecular_function	identical protein binding
B	0009036	molecular_function	type II site-specific deoxyribonuclease activity
B	0042802	molecular_function	identical protein binding
C	0009036	molecular_function	type II site-specific deoxyribonuclease activity
C	0042802	molecular_function	identical protein binding
D	0009036	molecular_function	type II site-specific deoxyribonuclease activity
D	0042802	molecular_function	identical protein binding
E	0009036	molecular_function	type II site-specific deoxyribonuclease activity
E	0042802	molecular_function	identical protein binding
F	0009036	molecular_function	type II site-specific deoxyribonuclease activity
F	0042802	molecular_function	identical protein binding
G	0009036	molecular_function	type II site-specific deoxyribonuclease activity
G	0042802	molecular_function	identical protein binding
H	0009036	molecular_function	type II site-specific deoxyribonuclease activity
H	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 E 215

Chain	Residue
E	ARG8
E	SER9

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PO4 B 215

Chain	Residue
B	HIS194

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 D 215

Chain	Residue
D	LYS174
D	HIS194

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 G 215

Chain	Residue
G	ARG8
G	SER9

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 F 215

Chain	Residue
F	TYR57
F	ASN117

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 F 216

Chain	Residue
F	GLU107
F	HIS163
F	THR164
F	TRP186
F	HOH452
O	DG7
O	DC8

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 D 216

Chain	Residue
D	SER195
D	GLU196
D	PHE199
D	ARG203

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 A 215

Chain	Residue
A	HIS56
A	ARG68

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 H 215

Chain	Residue
C	SER209
C	LYS210
H	LYS174
H	HIS194

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 H 216

Chain	Residue
C	ARG65
H	SER195
H	GLU196
H	PHE199
H	ARG203

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 B 216

Chain	Residue
B	HIS56
B	ARG68

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"20800503","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	Active site: {"evidences":[{"source":"PubMed","id":"20800503","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20800503","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20800503","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MX4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NIC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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