3NIA

GES-2 carbapenemase tazobactam complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE TBE A 288

Chain	Residue
A	CYS63
A	HOH386
A	HOH404
A	HOH444
A	HOH519
A	HOH555
A	HOH573
A	SER64
A	ASN127
A	PRO162
A	ASN165
A	GLY231
A	THR232
A	TF7289
A	HOH385

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE TF7 A 289

Chain	Residue
A	SER64
A	TRP99
A	SER125
A	THR211
A	LYS229
A	THR230
A	GLY231
A	THR232
A	ARG238
A	TBE288
A	HOH383
A	HOH385
A	HOH386
A	HOH400
A	HOH558

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile; acyl-ester intermediate => ECO:0000250|UniProtKB:A0A5R8T042

Chain	Residue	Details
A	SER64

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0A5R8T042

Chain	Residue	Details
A	LYS67
A	SER125
A	GLU161

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