3NAQ
Apo-form of NAD-dependent formate dehydrogenase from higher-plant Arabidopsis thaliana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
| A | 0009507 | cellular_component | chloroplast |
| A | 0009536 | cellular_component | plastid |
| A | 0009579 | cellular_component | thylakoid |
| A | 0009611 | biological_process | response to wounding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0032787 | biological_process | monocarboxylic acid metabolic process |
| A | 0042183 | biological_process | formate catabolic process |
| A | 0051287 | molecular_function | NAD binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005829 | cellular_component | cytosol |
| B | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
| B | 0009507 | cellular_component | chloroplast |
| B | 0009536 | cellular_component | plastid |
| B | 0009579 | cellular_component | thylakoid |
| B | 0009611 | biological_process | response to wounding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0032787 | biological_process | monocarboxylic acid metabolic process |
| B | 0042183 | biological_process | formate catabolic process |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1 |
| Chain | Residue |
| A | ARG354 |
| A | PRO362 |
| A | HOH396 |
| A | HOH479 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 18 |
| Chain | Residue |
| A | GLU359 |
| A | ASP360 |
| A | HOH418 |
| A | HOH581 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 20 |
| Chain | Residue |
| A | ARG185 |
| B | LYS45 |
| A | TYR184 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2 |
| Chain | Residue |
| B | ARG354 |
| B | HOH432 |
| B | HOH549 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 3 |
| Chain | Residue |
| B | GLU359 |
| B | ASP360 |
| B | HOH455 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 19 |
| Chain | Residue |
| B | TYR184 |
| B | ARG185 |
| B | ASN326 |
| B | HOH558 |
Functional Information from PROSITE/UniProt
| site_id | PS00065 |
| Number of Residues | 28 |
| Details | D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. IGTVGaGRIGklllqrlkpfgcn.LLyHD |
| Chain | Residue | Details |
| A | ILE194-ASP221 |
| site_id | PS00670 |
| Number of Residues | 23 |
| Details | D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. MLpkCDVIvINmPltekTrgMfN |
| Chain | Residue | Details |
| A | MET244-ASN266 |
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. LKkGvLIVNnARGaIME |
| Chain | Residue | Details |
| A | LEU273-GLU289 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03210","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2010","submissionDatabase":"PDB data bank","title":"Structures of the apo and holo forms of NAD-dependent formate dehydrogenase from the higher-plant Arabidopsis thaliana.","authors":["Shabalin I.G.","Polyakov K.M.","Skirgello O.E.","Tishkov V.I.","Popov V.O."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
