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3NAM

SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0005215molecular_functiontransporter activity
A0005388molecular_functionP-type calcium transporter activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0006816biological_processcalcium ion transport
A0006874biological_processintracellular calcium ion homeostasis
A0016020cellular_componentmembrane
A0016529cellular_componentsarcoplasmic reticulum
A0016887molecular_functionATP hydrolysis activity
A0033017cellular_componentsarcoplasmic reticulum membrane
A0046872molecular_functionmetal ion binding
A0070588biological_processcalcium ion transmembrane transport
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA A 995
ChainResidue
AGLN244
ALEU711
ALYS712
AALA714
AGLU732

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 996
ChainResidue
AASP703
AASP707
AHOH1000

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE OTK A 997
ChainResidue
APHE256
AGLN259
ALEU260
AVAL263
AVAL769
AVAL772
AILE829
APHE834
ATYR837
AGLU255

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PTY A 998
ChainResidue
AASN101
AVAL104
AGLY105
APRO312
AALA313
ATHR316

Functional Information from PROSITE/UniProt
site_idPS00154
Number of Residues7
DetailsATPASE_E1_E2 E1-E2 ATPases phosphorylation site. DKTGTLT
ChainResidueDetails
AASP351-THR357

226707

PDB entries from 2024-10-30

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