Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 218 |
| Chain | Residue |
| A | TYR18 |
| A | 93N221 |
| A | 93N221 |
| A | HOH500 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 219 |
| Chain | Residue |
| A | SER89 |
| A | TYR90 |
| A | GLN100 |
| B | LYS44 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 935 A 220 |
| Chain | Residue |
| A | GLY23 |
| A | CYS25 |
| A | ASN67 |
| A | GLY68 |
| A | MET71 |
| A | GLY137 |
| A | VAL162 |
| A | ASN163 |
| A | GLY165 |
| A | HOH327 |
| A | HOH362 |
| A | HOH415 |
| A | GLN19 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 93N A 221 |
| Chain | Residue |
| A | TYR18 |
| A | TYR18 |
| A | GLN19 |
| A | GLY20 |
| A | GLY20 |
| A | PHE146 |
| A | LEU147 |
| A | LEU147 |
| A | ARG149 |
| A | TRP186 |
| A | ASN189 |
| A | PEG218 |
| A | PEG218 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 B 218 |
| Chain | Residue |
| B | LYS82 |
| B | SER103 |
| B | SER103 |
| B | ARG106 |
| B | ARG106 |
| B | HOH365 |
| B | HOH365 |
| B | HOH369 |
| B | HOH370 |
| B | HOH370 |
| B | HOH415 |
| B | HOH415 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 219 |
| Chain | Residue |
| B | THR14 |
| B | GLU15 |
| B | SER47 |
| B | HOH287 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 220 |
| Chain | Residue |
| A | HOH275 |
| B | VAL16 |
| B | HIS188 |
| B | HOH273 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 935 B 221 |
| Chain | Residue |
| B | GLY23 |
| B | CYS25 |
| B | GLY68 |
| B | MET71 |
| B | GLY137 |
| B | VAL162 |
| B | ASN163 |
| B | HIS164 |
| B | GLY165 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGACWAfSA |
| Chain | Residue | Details |
| A | GLN19-ALA30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHGVLVVGYG |
| Chain | Residue | Details |
| A | VAL162-GLY172 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWghnFGeeGYIrM |
| Chain | Residue | Details |
| A | TYR179-MET198 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| A | GLN19 | electrostatic stabiliser |
| A | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | HIS164 | proton acceptor, proton donor |
| A | ASN184 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| B | GLN19 | electrostatic stabiliser |
| B | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | HIS164 | proton acceptor, proton donor |
| B | ASN184 | electrostatic stabiliser |
