3N1T
Crystal structure of the H101A mutant ecHint GMP complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043530 | molecular_function | adenosine 5'-monophosphoramidase activity |
| A | 0055130 | biological_process | D-alanine catabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0043530 | molecular_function | adenosine 5'-monophosphoramidase activity |
| B | 0055130 | biological_process | D-alanine catabolic process |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0042803 | molecular_function | protein homodimerization activity |
| E | 0043530 | molecular_function | adenosine 5'-monophosphoramidase activity |
| E | 0055130 | biological_process | D-alanine catabolic process |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0042803 | molecular_function | protein homodimerization activity |
| F | 0043530 | molecular_function | adenosine 5'-monophosphoramidase activity |
| F | 0055130 | biological_process | D-alanine catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 5GP A 200 |
| Chain | Residue |
| A | ILE6 |
| A | GLU96 |
| A | VAL97 |
| A | HIS103 |
| A | HOH127 |
| A | HOH132 |
| A | HOH179 |
| A | HOH184 |
| A | ILE10 |
| A | ARG30 |
| A | ASP31 |
| A | ILE32 |
| A | SER33 |
| A | LEU41 |
| A | ASN88 |
| A | GLN95 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 5GP B 200 |
| Chain | Residue |
| A | ARG13 |
| A | HOH183 |
| B | ILE6 |
| B | PHE29 |
| B | ARG30 |
| B | ASP31 |
| B | ILE32 |
| B | LEU41 |
| B | ASN88 |
| B | GLN95 |
| B | GLU96 |
| B | VAL97 |
| B | HIS103 |
| B | HOH121 |
| B | HOH125 |
| B | HOH134 |
| B | HOH141 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 5GP E 200 |
| Chain | Residue |
| E | ILE6 |
| E | ARG30 |
| E | ASP31 |
| E | ILE32 |
| E | SER33 |
| E | LEU41 |
| E | ASN88 |
| E | GLN95 |
| E | GLU96 |
| E | VAL97 |
| E | HIS103 |
| E | HOH121 |
| E | HOH140 |
| E | HOH145 |
| E | HOH147 |
| E | HOH164 |
| F | ARG13 |
| F | HOH185 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 5GP F 200 |
| Chain | Residue |
| F | ILE6 |
| F | PHE7 |
| F | ILE10 |
| F | ARG30 |
| F | ASP31 |
| F | ILE32 |
| F | LEU41 |
| F | ASN88 |
| F | GLN95 |
| F | GLU96 |
| F | VAL97 |
| F | HIS103 |
| F | HOH123 |
| F | HOH129 |
| F | HOH133 |
| F | HOH156 |
| F | HOH161 |
| F | HOH164 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 436 |
| Details | Domain: {"description":"HIT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00464","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Motif: {"description":"Histidine triad motif","evidences":[{"source":"PubMed","id":"20934431","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Tele-AMP-histidine intermediate","evidences":[{"source":"PubMed","id":"15703176","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20934431","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20934431","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3N1S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
