3MU3
Crystal structure of chicken MD-1 complexed with lipid IVa
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002376 | biological_process | immune system process |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006954 | biological_process | inflammatory response |
| A | 0006955 | biological_process | immune response |
| A | 0031666 | biological_process | positive regulation of lipopolysaccharide-mediated signaling pathway |
| A | 0045087 | biological_process | innate immune response |
| B | 0002376 | biological_process | immune system process |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006954 | biological_process | inflammatory response |
| B | 0006955 | biological_process | immune response |
| B | 0031666 | biological_process | positive regulation of lipopolysaccharide-mediated signaling pathway |
| B | 0045087 | biological_process | innate immune response |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE LP4 A 300 |
| Chain | Residue |
| A | PHE48 |
| A | ALA137 |
| A | ALA150 |
| A | PHE152 |
| A | LP5301 |
| A | ALA78 |
| A | GLU94 |
| A | LYS103 |
| A | LEU104 |
| A | TYR117 |
| A | PRO120 |
| A | ILE121 |
| A | THR122 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE LP5 A 301 |
| Chain | Residue |
| A | ILE35 |
| A | LEU90 |
| A | TYR92 |
| A | GLY124 |
| A | PHE152 |
| A | HOH177 |
| A | HOH197 |
| A | LP4300 |
| B | ARG131 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 3 |
| Chain | Residue |
| A | HIS25 |
| A | ASP45 |
| A | ALA47 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE LP4 B 300 |
| Chain | Residue |
| B | PHE48 |
| B | ALA78 |
| B | TYR92 |
| B | GLU94 |
| B | LYS103 |
| B | LEU104 |
| B | TYR117 |
| B | PRO120 |
| B | ILE121 |
| B | THR122 |
| B | LP5301 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE LP5 B 301 |
| Chain | Residue |
| A | ARG131 |
| B | ILE35 |
| B | LEU90 |
| B | TYR92 |
| B | GLY124 |
| B | PHE152 |
| B | HOH197 |
| B | LP4300 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1 |
| Chain | Residue |
| A | HIS25 |
| A | THR26 |
| B | TYR116 |
| B | TYR117 |
| B | GLU118 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 2 |
| Chain | Residue |
| A | TYR117 |
| A | GLU118 |
| B | HIS25 |
| B | THR26 |
