3MOW
Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE B2B A 1 |
| Chain | Residue |
| A | HOH3 |
| A | SER460 |
| A | ALA461 |
| A | GLY464 |
| A | ARG465 |
| A | GLN506 |
| A | HOH126 |
| A | ARG278 |
| A | TYR279 |
| A | LEU334 |
| A | GLN335 |
| A | LYS366 |
| A | MET450 |
| A | CYS459 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
| Chain | Residue | Details |
| A | VAL457-GLY467 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Phosphocysteine intermediate"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
