3MCA

Structure of the Dom34-Hbs1 Complex and implications for its role in No-Go decay

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002184	biological_process	cytoplasmic translational termination
A	0003747	molecular_function	translation release factor activity
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0030968	biological_process	endoplasmic reticulum unfolded protein response
A	0032790	biological_process	ribosome disassembly
A	0045948	biological_process	positive regulation of translational initiation
A	0070966	biological_process	nuclear-transcribed mRNA catabolic process, no-go decay
A	0072344	biological_process	rescue of stalled cytosolic ribosome
A	1990533	cellular_component	Dom34-Hbs1 complex
B	0002181	biological_process	cytoplasmic translation
B	0002184	biological_process	cytoplasmic translational termination
B	0003747	molecular_function	translation release factor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0022626	cellular_component	cytosolic ribosome
B	0030695	molecular_function	GTPase regulator activity
B	0030968	biological_process	endoplasmic reticulum unfolded protein response
B	0032790	biological_process	ribosome disassembly
B	0045948	biological_process	positive regulation of translational initiation
B	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay
B	0070966	biological_process	nuclear-transcribed mRNA catabolic process, no-go decay
B	0071025	biological_process	RNA surveillance
B	0072344	biological_process	rescue of stalled cytosolic ribosome
B	0170011	molecular_function	stalled ribosome sensor activity
B	1990533	cellular_component	Dom34-Hbs1 complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P32769","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---