3MAV

Crystal structure of Plasmodium vivax putative farnesyl pyrophosphate synthase (Pv092040)

Replaces:  2IHI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004161	molecular_function	dimethylallyltranstransferase activity
A	0004337	molecular_function	geranyltranstransferase activity
A	0005737	cellular_component	cytoplasm
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0045337	biological_process	farnesyl diphosphate biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0004161	molecular_function	dimethylallyltranstransferase activity
B	0004337	molecular_function	geranyltranstransferase activity
B	0005737	cellular_component	cytoplasm
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0045337	biological_process	farnesyl diphosphate biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0004161	molecular_function	dimethylallyltranstransferase activity
C	0004337	molecular_function	geranyltranstransferase activity
C	0005737	cellular_component	cytoplasm
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016020	cellular_component	membrane
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0045337	biological_process	farnesyl diphosphate biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0004161	molecular_function	dimethylallyltranstransferase activity
D	0004337	molecular_function	geranyltranstransferase activity
D	0005737	cellular_component	cytoplasm
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016020	cellular_component	membrane
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0045337	biological_process	farnesyl diphosphate biosynthetic process
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 2003

Chain	Residue
A	LYS80
A	GLN118
A	ARG135
A	HOH715
A	HOH742

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 2005

Chain	Residue
A	ARG171
A	ASN172

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 2002

Chain	Residue
B	ARG135
B	HOH425
B	HOH749
B	LYS80
B	GLN118

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 2008

Chain	Residue
B	TYR93
B	TYR382

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 2009

Chain	Residue
B	ASP41
B	ARG44
B	LYS69

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 2010

Chain	Residue
B	GLU147
B	THR148
B	HOH409
B	HOH450

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 2011

Chain	Residue
C	ASP41
C	ARG44
C	ASP73

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site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 2001

Chain	Residue
D	LYS80
D	GLN118
D	ARG135
D	HOH403
D	HOH425
D	HOH426
D	HOH472

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site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 2004

Chain	Residue
C	LYS130
D	GLU147
D	THR148
D	HOH415
D	HOH428
D	HOH575
D	HOH767

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Functional Information from PROSITE/UniProt

site_id	PS00444
Number of Residues	13
Details	POLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. MGeyFQIhDDYlD

Chain	Residue	Details
A	MET278-ASP290

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