3M6V
Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus in space group P2 in complex with S-Adenosyl-L-Methionine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000470 | biological_process | maturation of LSU-rRNA |
| A | 0001510 | biological_process | RNA methylation |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006364 | biological_process | rRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008173 | molecular_function | RNA methyltransferase activity |
| A | 0009383 | molecular_function | rRNA (cytosine-C5-)-methyltransferase activity |
| A | 0016428 | molecular_function | tRNA (cytidine-5-)-methyltransferase activity |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0032259 | biological_process | methylation |
| A | 0070475 | biological_process | rRNA base methylation |
| B | 0000470 | biological_process | maturation of LSU-rRNA |
| B | 0001510 | biological_process | RNA methylation |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006364 | biological_process | rRNA processing |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008173 | molecular_function | RNA methyltransferase activity |
| B | 0009383 | molecular_function | rRNA (cytosine-C5-)-methyltransferase activity |
| B | 0016428 | molecular_function | tRNA (cytidine-5-)-methyltransferase activity |
| B | 0030488 | biological_process | tRNA methylation |
| B | 0032259 | biological_process | methylation |
| B | 0070475 | biological_process | rRNA base methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAM A 465 |
| Chain | Residue |
| A | ALA109 |
| A | ARG138 |
| A | PRO160 |
| A | ASP177 |
| A | ALA178 |
| A | PRO179 |
| A | LEU211 |
| A | HOH529 |
| A | HOH531 |
| A | HOH547 |
| A | HOH707 |
| A | ALA110 |
| A | HOH785 |
| A | HOH905 |
| A | HOH953 |
| A | HOH1151 |
| A | ALA111 |
| A | PRO112 |
| A | GLY113 |
| A | GLY114 |
| A | LYS115 |
| A | GLU133 |
| A | VAL134 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAM B 465 |
| Chain | Residue |
| B | ALA109 |
| B | ALA110 |
| B | ALA111 |
| B | PRO112 |
| B | GLY113 |
| B | GLY114 |
| B | LYS115 |
| B | GLU133 |
| B | VAL134 |
| B | ARG138 |
| B | ASP177 |
| B | ALA178 |
| B | PRO179 |
| B | LEU211 |
| B | HOH498 |
| B | HOH508 |
| B | HOH615 |
| B | HOH719 |
| B | HOH853 |
| B | HOH891 |
| B | HOH1090 |
| B | HOH1209 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU01023 |
| Chain | Residue | Details |
| A | CYS230 | |
| B | CYS230 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20558545 |
| Chain | Residue | Details |
| B | ARG138 | |
| B | ASP177 | |
| A | ALA109 | |
| A | GLU133 | |
| A | ARG138 | |
| A | ASP177 | |
| B | ALA109 | |
| B | GLU133 |
