3M1N
Crystal structure of Human Sonic Hedgehog N-terminal domain
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 200 |
| Chain | Residue |
| A | HIS140 |
| A | ASP147 |
| A | GLU176 |
| A | HIS182 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 701 |
| Chain | Residue |
| A | ARG163 |
| A | HOH211 |
| A | HOH242 |
| A | HOH248 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 702 |
| Chain | Residue |
| A | ARG123 |
| A | ARG153 |
| A | HOH719 |
| A | LYS87 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 705 |
| Chain | Residue |
| A | ARG101 |
| A | LYS105 |
| A | HOH250 |
| A | HOH272 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 700 |
| Chain | Residue |
| B | HIS140 |
| B | ASP147 |
| B | HIS182 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 201 |
| Chain | Residue |
| B | ARG163 |
| B | HOH199 |
| B | HOH220 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 202 |
| Chain | Residue |
| B | HOH16 |
| B | ARG28 |
| B | GLY29 |
| B | PHE30 |
| B | GLY31 |
| B | ARG33 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 703 |
| Chain | Residue |
| B | ARG33 |
| B | ARG34 |
| B | HIS35 |
| B | HOH319 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 704 |
| Chain | Residue |
| B | LYS87 |
| B | ARG123 |
| B | ARG153 |
| B | HOH213 |
| B | HOH259 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1 |
| Chain | Residue |
| B | HIS35 |
| B | GLY60 |
| B | ARG61 |
| B | HOH203 |
| B | HOH319 |
| B | HOH339 |
| B | HOH530 |
| B | HOH566 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2 |
| Chain | Residue |
| B | ARG101 |
| B | LYS105 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Motif: {"description":"Cardin-Weintraub","evidences":[{"source":"PubMed","id":"23118222","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20504762","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MXW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10753901","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20504762","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3M1N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MXW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
