3LVW
Glutathione-inhibited ScGCL
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004357 | molecular_function | glutamate-cysteine ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006750 | biological_process | glutathione biosynthetic process |
A | 0016874 | molecular_function | ligase activity |
A | 0042542 | biological_process | response to hydrogen peroxide |
A | 0046686 | biological_process | response to cadmium ion |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GSH A 693 |
Chain | Residue |
A | GLU52 |
A | ILE317 |
A | TYR362 |
A | TRP445 |
A | ARG472 |
A | HOH789 |
A | HOH834 |
A | HOH860 |
A | GLU96 |
A | ARG196 |
A | PHE197 |
A | MET262 |
A | CYS264 |
A | CYS266 |
A | GLN268 |
A | ARG313 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PGE A 694 |
Chain | Residue |
A | GLY163 |
A | CYS164 |
A | PRO165 |
A | ASP166 |
A | PRO173 |
A | TRP174 |
A | PHE185 |
A | TYR232 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE PGE A 695 |
Chain | Residue |
A | GLY48 |
A | PRO106 |
A | ALA107 |
A | PRO109 |
A | ARG468 |
A | HOH852 |
A | HOH856 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PGE A 696 |
Chain | Residue |
A | GLY38 |
A | ASP41 |
A | ASN275 |
A | ASN277 |
A | HOH861 |