3LVW
Glutathione-inhibited ScGCL
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004357 | molecular_function | glutamate-cysteine ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006750 | biological_process | glutathione biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0042542 | biological_process | response to hydrogen peroxide |
| A | 0046686 | biological_process | response to cadmium ion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GSH A 693 |
| Chain | Residue |
| A | GLU52 |
| A | ILE317 |
| A | TYR362 |
| A | TRP445 |
| A | ARG472 |
| A | HOH789 |
| A | HOH834 |
| A | HOH860 |
| A | GLU96 |
| A | ARG196 |
| A | PHE197 |
| A | MET262 |
| A | CYS264 |
| A | CYS266 |
| A | GLN268 |
| A | ARG313 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PGE A 694 |
| Chain | Residue |
| A | GLY163 |
| A | CYS164 |
| A | PRO165 |
| A | ASP166 |
| A | PRO173 |
| A | TRP174 |
| A | PHE185 |
| A | TYR232 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PGE A 695 |
| Chain | Residue |
| A | GLY48 |
| A | PRO106 |
| A | ALA107 |
| A | PRO109 |
| A | ARG468 |
| A | HOH852 |
| A | HOH856 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 696 |
| Chain | Residue |
| A | GLY38 |
| A | ASP41 |
| A | ASN275 |
| A | ASN277 |
| A | HOH861 |
