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3LSY

Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T0

Functional Information from GO Data
ChainGOidnamespacecontents
A0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
A0006633biological_processfatty acid biosynthetic process
B0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
B0006633biological_processfatty acid biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues24
DetailsBINDING SITE FOR RESIDUE NAD A 501
ChainResidue
AGLY104
ASER215
ALEU216
AALA217
AASN218
ALEU265
ATHR266
ATYR267
ALYS285
AALA312
AGLY313
AGLY106
APRO314
ALEU315
ASER317
AALA319
AFT0502
AGLY110
ATYR111
ATRP131
APHE167
AASP168
AALA169
ASER170

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE FT0 A 502
ChainResidue
AALA217
AVAL222
ATYR277
APRO314
ANAD501

site_idAC3
Number of Residues22
DetailsBINDING SITE FOR RESIDUE NAD B 601
ChainResidue
BGLY104
BILE105
BGLY106
BGLY110
BTYR111
BTRP131
BPHE167
BASP168
BALA169
BLEU216
BALA217
BLEU265
BTHR266
BTYR267
BLYS285
BALA312
BGLY313
BPRO314
BLEU315
BSER317
BALA319
BFT0602

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE FT0 B 602
ChainResidue
BALA217
BTYR277
BMET281
BALA319
BNAD601

227111

PDB entries from 2024-11-06

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