Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006865 | biological_process | amino acid transport |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006865 | biological_process | amino acid transport |
| B | 0015297 | molecular_function | antiporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006865 | biological_process | amino acid transport |
| C | 0015297 | molecular_function | antiporter activity |
| C | 0016020 | cellular_component | membrane |
| C | 0022857 | molecular_function | transmembrane transporter activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006865 | biological_process | amino acid transport |
| D | 0015297 | molecular_function | antiporter activity |
| D | 0016020 | cellular_component | membrane |
| D | 0022857 | molecular_function | transmembrane transporter activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 440 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-LEU12 | |
| B | GLY143 | |
| B | GLU208-ILE226 | |
| B | LYS302-PRO323 | |
| B | ALA371-LEU388 | |
| B | ASN427-ASP445 | |
| C | MET1-LEU12 | |
| C | LYS62-GLY86 | |
| C | GLY143 | |
| C | GLU208-ILE226 | |
| C | LYS302-PRO323 | |
| A | LYS62-GLY86 | |
| C | ALA371-LEU388 | |
| C | ASN427-ASP445 | |
| D | MET1-LEU12 | |
| D | LYS62-GLY86 | |
| D | GLY143 | |
| D | GLU208-ILE226 | |
| D | LYS302-PRO323 | |
| D | ALA371-LEU388 | |
| D | ASN427-ASP445 | |
| A | GLY143 | |
| A | GLU208-ILE226 | |
| A | LYS302-PRO323 | |
| A | ALA371-LEU388 | |
| A | ASN427-ASP445 | |
| B | MET1-LEU12 | |
| B | LYS62-GLY86 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 876 |
| Details | TRANSMEM: Helical => ECO:0007744|PDB:3L1L |
| Chain | Residue | Details |
| A | ILE13-MET24 | |
| A | VAL353-ALA370 | |
| A | ALA389-GLY404 | |
| A | LYS408-LEU426 | |
| B | ILE13-MET24 | |
| B | ILE43-ALA61 | |
| B | TYR87-LEU112 | |
| B | LEU125-VAL142 | |
| B | PRO144-PHE171 | |
| B | SER195-VAL207 | |
| B | ALA227-MET247 | |
| A | ILE43-ALA61 | |
| B | VAL278-ALA301 | |
| B | VAL324-SER340 | |
| B | VAL353-ALA370 | |
| B | ALA389-GLY404 | |
| B | LYS408-LEU426 | |
| C | ILE13-MET24 | |
| C | ILE43-ALA61 | |
| C | TYR87-LEU112 | |
| C | LEU125-VAL142 | |
| C | PRO144-PHE171 | |
| A | TYR87-LEU112 | |
| C | SER195-VAL207 | |
| C | ALA227-MET247 | |
| C | VAL278-ALA301 | |
| C | VAL324-SER340 | |
| C | VAL353-ALA370 | |
| C | ALA389-GLY404 | |
| C | LYS408-LEU426 | |
| D | ILE13-MET24 | |
| D | ILE43-ALA61 | |
| D | TYR87-LEU112 | |
| A | LEU125-VAL142 | |
| D | LEU125-VAL142 | |
| D | PRO144-PHE171 | |
| D | SER195-VAL207 | |
| D | ALA227-MET247 | |
| D | VAL278-ALA301 | |
| D | VAL324-SER340 | |
| D | VAL353-ALA370 | |
| D | ALA389-GLY404 | |
| D | LYS408-LEU426 | |
| A | PRO144-PHE171 | |
| A | SER195-VAL207 | |
| A | ALA227-MET247 | |
| A | VAL278-ALA301 | |
| A | VAL324-SER340 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 368 |
| Details | TOPO_DOM: Periplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY25-ALA42 | |
| B | GLY248-ILE277 | |
| B | SER341-LEU352 | |
| B | SER405-ALA407 | |
| C | GLY25-ALA42 | |
| C | SER113-VAL124 | |
| C | TRP172-GLN194 | |
| C | GLY248-ILE277 | |
| C | SER341-LEU352 | |
| C | SER405-ALA407 | |
| D | GLY25-ALA42 | |
| A | SER113-VAL124 | |
| D | SER113-VAL124 | |
| D | TRP172-GLN194 | |
| D | GLY248-ILE277 | |
| D | SER341-LEU352 | |
| D | SER405-ALA407 | |
| A | TRP172-GLN194 | |
| A | GLY248-ILE277 | |
| A | SER341-LEU352 | |
| A | SER405-ALA407 | |
| B | GLY25-ALA42 | |
| B | SER113-VAL124 | |
| B | TRP172-GLN194 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20090677, ECO:0007744|PDB:3L1L |
| Chain | Residue | Details |
| A | ILE23 | |
| B | GLY27 | |
| B | ALA96 | |
| B | CYS97 | |
| B | TRP202 | |
| B | TRP293 | |
| C | ILE23 | |
| C | SER26 | |
| C | GLY27 | |
| C | ALA96 | |
| C | CYS97 | |
| A | SER26 | |
| C | TRP202 | |
| C | TRP293 | |
| D | ILE23 | |
| D | SER26 | |
| D | GLY27 | |
| D | ALA96 | |
| D | CYS97 | |
| D | TRP202 | |
| D | TRP293 | |
| A | GLY27 | |
| A | ALA96 | |
| A | CYS97 | |
| A | TRP202 | |
| A | TRP293 | |
| B | ILE23 | |
| B | SER26 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20090677 |
| Chain | Residue | Details |
| A | ASN101 | |
| D | ASN101 | |
| D | ILE205 | |
| D | SER357 | |
| A | ILE205 | |
| A | SER357 | |
| B | ASN101 | |
| B | ILE205 | |
| B | SER357 | |
| C | ASN101 | |
| C | ILE205 | |
| C | SER357 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | SITE: Cytoplasmic (distal) gate => ECO:0000305|PubMed:20090677 |
| Chain | Residue | Details |
| A | TYR93 | |
| D | TYR93 | |
| D | GLU208 | |
| D | TYR365 | |
| A | GLU208 | |
| A | TYR365 | |
| B | TYR93 | |
| B | GLU208 | |
| B | TYR365 | |
| C | TYR93 | |
| C | GLU208 | |
| C | TYR365 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | SITE: Periplasmic (proximal) gate => ECO:0000269|PubMed:20090677 |
| Chain | Residue | Details |
| A | TRP202 | |
| B | TRP202 | |
| C | TRP202 | |
| D | TRP202 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | SITE: Middle gate => ECO:0000305|PubMed:20090677 |
| Chain | Residue | Details |
| A | TRP293 | |
| B | TRP293 | |
| C | TRP293 | |
| D | TRP293 |
