3LMV

D-Tyr-tRNA(Tyr) Deacylase from plasmodium falciparum in complex with hepes

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002161	molecular_function	aminoacyl-tRNA deacylase activity
A	0005737	cellular_component	cytoplasm
A	0006399	biological_process	tRNA metabolic process
A	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
A	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
A	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
A	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
B	0002161	molecular_function	aminoacyl-tRNA deacylase activity
B	0005737	cellular_component	cytoplasm
B	0006399	biological_process	tRNA metabolic process
B	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
B	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
B	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
B	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
C	0002161	molecular_function	aminoacyl-tRNA deacylase activity
C	0005737	cellular_component	cytoplasm
C	0006399	biological_process	tRNA metabolic process
C	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
C	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
C	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
C	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
D	0002161	molecular_function	aminoacyl-tRNA deacylase activity
D	0005737	cellular_component	cytoplasm
D	0006399	biological_process	tRNA metabolic process
D	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
D	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
D	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
D	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
E	0002161	molecular_function	aminoacyl-tRNA deacylase activity
E	0005737	cellular_component	cytoplasm
E	0006399	biological_process	tRNA metabolic process
E	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
E	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
E	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
E	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
F	0002161	molecular_function	aminoacyl-tRNA deacylase activity
F	0005737	cellular_component	cytoplasm
F	0006399	biological_process	tRNA metabolic process
F	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
F	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
F	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
F	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE B 165

Chain	Residue
A	ARG7
A	GLY149
A	PRO150
B	SER87
B	GLN88
B	PHE89
B	GLY138
B	ASN139

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE D 165

Chain	Residue
C	ASN66
C	GLY149
D	SER87
D	GLN88
D	PHE89
D	GLY138
D	ASN139
C	ARG7

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE A 165

Chain	Residue
A	SER87
A	GLN88
A	PHE89
A	GLY138
A	ASN139
B	ARG7
B	ASN66
B	PRO150

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EPE C 165

Chain	Residue
C	SER87
C	PHE89
C	GLY138
C	ASN139
C	TYR140
D	ARG7
D	GLY149

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EPE B 166

Chain	Residue
B	GLU122
C	ASN110
C	LEU113
C	ASN139

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO3 B 167

Chain	Residue
B	ARG16
B	TYR140

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO3 F 165

Chain	Residue
F	SER87
F	GLN88
F	PHE89
F	GLY138

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO3 B 168

Chain	Residue
B	SER31
B	GLU32
B	LYS133

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	Motif: {"description":"C-terminal adenosine nucleotide of tRNA","evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3KO4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Motif: {"description":"Gly-cisPro motif, allows the protein to recognize chirality of D-amino acids","evidences":[{"source":"PubMed","id":"24302572","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3KO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3KO4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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