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3LMP

Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR RESIDUE CEK A 23
ChainResidue
AHOH13
AILE341
ASER342
ALEU353
ALYS367
AHOH478
AHOH174
AILE262
ALYS263
AGLY284
ACYS285
APHE287
AARG288
ASER289

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CSER698
AHIS323
AHIS449
ATYR473

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
ALYS224

218853

PDB entries from 2024-04-24

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