3LL5

Crystal structure of T. acidophilum isopentenyl phosphate kinase product complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016301	molecular_function	kinase activity
A	0102043	molecular_function	isopentenyl phosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016301	molecular_function	kinase activity
B	0102043	molecular_function	isopentenyl phosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016301	molecular_function	kinase activity
C	0102043	molecular_function	isopentenyl phosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016301	molecular_function	kinase activity
D	0102043	molecular_function	isopentenyl phosphate kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ADP A 246

Chain	Residue
A	LYS5
A	ASP172
A	PRO173
A	LYS174
A	ILE202
A	LYS205
A	IPE247
A	HOH251
A	HOH299
A	GLY7
A	GLY8
A	SER9
A	LYS14
A	THR163
A	ASP164
A	GLY167
A	TYR169

---

site_id	AC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE IPE A 247

Chain	Residue
A	LYS5
A	GLY8
A	LYS14
A	GLY44
A	GLY45
A	GLY46
A	GLY49
A	HIS50
A	GLY128
A	SER142
A	GLY143
A	ADP246
A	HOH291
A	HOH306

---

site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ADP B 246

Chain	Residue
A	GLU237
B	LYS5
B	GLY7
B	GLY8
B	SER9
B	LYS14
B	THR163
B	ASP164
B	GLY167
B	TYR169
B	LYS171
B	ASP172
B	LYS174
B	GLY201
B	ILE202
B	LYS205
B	IPE247
B	HOH250
B	HOH284

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE IPE B 247

Chain	Residue
B	LYS5
B	GLY8
B	LYS14
B	GLY44
B	GLY45
B	GLY46
B	GLY49
B	HIS50
B	GLY128
B	ILE140
B	SER142
B	GLY143
B	ADP246
B	HOH272
B	HOH290

---

site_id	AC5
Number of Residues	21
Details	BINDING SITE FOR RESIDUE ATP C 246

Chain	Residue
C	LYS5
C	GLY7
C	GLY8
C	SER9
C	GLY44
C	GLY46
C	HIS50
C	ASP164
C	GLY167
C	TYR169
C	LYS171
C	ASP172
C	PRO173
C	LYS174
C	GLY201
C	ILE202
C	LYS205
C	IP8247
C	HOH264
C	HOH269
C	HOH297

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE IP8 C 247

Chain	Residue
C	LYS5
C	GLY44
C	GLY45
C	GLY46
C	HIS50
C	GLY143
C	ATP246
C	HOH271
C	HOH275
C	HOH279
C	HOH311

---

site_id	AC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE ATP D 246

Chain	Residue
D	GLY8
D	SER9
D	GLY44
D	GLY46
D	HIS50
D	ASP164
D	GLY167
D	TYR169
D	LYS171
D	ASP172
D	PRO173
D	LYS174
D	ILE202
D	LYS205
D	IP8247
D	HOH279
D	HOH284
D	HOH285
D	LYS5
D	GLY7

---

site_id	AC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE IP8 D 247

Chain	Residue
D	LYS5
D	GLY44
D	GLY45
D	GLY46
D	GLY49
D	HIS50
D	GLY128
D	ATP246
D	HOH262
D	HOH263
D	HOH272
D	HOH281
D	HOH293

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING:

Chain	Residue	Details
A	LYS5
B	LYS5
B	GLY45
B	GLY46
B	HIS50
B	GLY143
B	ASP164
B	TYR169
B	GLY201
B	LYS205
C	LYS5
A	GLY45
C	GLY45
C	GLY46
C	HIS50
C	GLY143
C	ASP164
C	TYR169
C	GLY201
C	LYS205
D	LYS5
D	GLY45
A	GLY46
D	GLY46
D	HIS50
D	GLY143
D	ASP164
D	TYR169
D	GLY201
D	LYS205
A	HIS50
A	GLY143
A	ASP164
A	TYR169
A	GLY201
A	LYS205

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Transition state stabilizer

Chain	Residue	Details
A	LYS14
B	LYS14
C	LYS14
D	LYS14

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