3LL5
Crystal structure of T. acidophilum isopentenyl phosphate kinase product complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016114 | biological_process | terpenoid biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0102043 | molecular_function | isopentenyl phosphate kinase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016114 | biological_process | terpenoid biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0102043 | molecular_function | isopentenyl phosphate kinase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0008299 | biological_process | isoprenoid biosynthetic process |
| C | 0016114 | biological_process | terpenoid biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0102043 | molecular_function | isopentenyl phosphate kinase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0008299 | biological_process | isoprenoid biosynthetic process |
| D | 0016114 | biological_process | terpenoid biosynthetic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0102043 | molecular_function | isopentenyl phosphate kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP A 246 |
| Chain | Residue |
| A | LYS5 |
| A | ASP172 |
| A | PRO173 |
| A | LYS174 |
| A | ILE202 |
| A | LYS205 |
| A | IPE247 |
| A | HOH251 |
| A | HOH299 |
| A | GLY7 |
| A | GLY8 |
| A | SER9 |
| A | LYS14 |
| A | THR163 |
| A | ASP164 |
| A | GLY167 |
| A | TYR169 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE IPE A 247 |
| Chain | Residue |
| A | LYS5 |
| A | GLY8 |
| A | LYS14 |
| A | GLY44 |
| A | GLY45 |
| A | GLY46 |
| A | GLY49 |
| A | HIS50 |
| A | GLY128 |
| A | SER142 |
| A | GLY143 |
| A | ADP246 |
| A | HOH291 |
| A | HOH306 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP B 246 |
| Chain | Residue |
| A | GLU237 |
| B | LYS5 |
| B | GLY7 |
| B | GLY8 |
| B | SER9 |
| B | LYS14 |
| B | THR163 |
| B | ASP164 |
| B | GLY167 |
| B | TYR169 |
| B | LYS171 |
| B | ASP172 |
| B | LYS174 |
| B | GLY201 |
| B | ILE202 |
| B | LYS205 |
| B | IPE247 |
| B | HOH250 |
| B | HOH284 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE IPE B 247 |
| Chain | Residue |
| B | LYS5 |
| B | GLY8 |
| B | LYS14 |
| B | GLY44 |
| B | GLY45 |
| B | GLY46 |
| B | GLY49 |
| B | HIS50 |
| B | GLY128 |
| B | ILE140 |
| B | SER142 |
| B | GLY143 |
| B | ADP246 |
| B | HOH272 |
| B | HOH290 |
| site_id | AC5 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ATP C 246 |
| Chain | Residue |
| C | LYS5 |
| C | GLY7 |
| C | GLY8 |
| C | SER9 |
| C | GLY44 |
| C | GLY46 |
| C | HIS50 |
| C | ASP164 |
| C | GLY167 |
| C | TYR169 |
| C | LYS171 |
| C | ASP172 |
| C | PRO173 |
| C | LYS174 |
| C | GLY201 |
| C | ILE202 |
| C | LYS205 |
| C | IP8247 |
| C | HOH264 |
| C | HOH269 |
| C | HOH297 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE IP8 C 247 |
| Chain | Residue |
| C | LYS5 |
| C | GLY44 |
| C | GLY45 |
| C | GLY46 |
| C | HIS50 |
| C | GLY143 |
| C | ATP246 |
| C | HOH271 |
| C | HOH275 |
| C | HOH279 |
| C | HOH311 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ATP D 246 |
| Chain | Residue |
| D | GLY8 |
| D | SER9 |
| D | GLY44 |
| D | GLY46 |
| D | HIS50 |
| D | ASP164 |
| D | GLY167 |
| D | TYR169 |
| D | LYS171 |
| D | ASP172 |
| D | PRO173 |
| D | LYS174 |
| D | ILE202 |
| D | LYS205 |
| D | IP8247 |
| D | HOH279 |
| D | HOH284 |
| D | HOH285 |
| D | LYS5 |
| D | GLY7 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE IP8 D 247 |
| Chain | Residue |
| D | LYS5 |
| D | GLY44 |
| D | GLY45 |
| D | GLY46 |
| D | GLY49 |
| D | HIS50 |
| D | GLY128 |
| D | ATP246 |
| D | HOH262 |
| D | HOH263 |
| D | HOH272 |
| D | HOH281 |
| D | HOH293 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 64 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Transition state stabilizer"} |
| Chain | Residue | Details |
