3LKJ

Small Molecule Inhibition of the TNF Family Cyokine CD40 Ligand Through a Subunit Fracture Mechanism

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LtVKrQGLYYIyaQVtF

Chain	Residue	Details
A	LEU161-PHE177

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (high mannose) asparagine; alternate","evidences":[{"source":"PubMed","id":"11676606","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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