3LK3

Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005886	cellular_component	plasma membrane
A	0008290	cellular_component	F-actin capping protein complex
A	0030018	cellular_component	Z disc
A	0030036	biological_process	actin cytoskeleton organization
A	0030863	cellular_component	cortical cytoskeleton
A	0034329	biological_process	cell junction assembly
A	0051015	molecular_function	actin filament binding
A	0051016	biological_process	barbed-end actin filament capping
A	0051693	biological_process	actin filament capping
A	0071203	cellular_component	WASH complex
B	0000902	biological_process	cell morphogenesis
B	0003779	molecular_function	actin binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005903	cellular_component	brush border
B	0007010	biological_process	cytoskeleton organization
B	0008154	biological_process	actin polymerization or depolymerization
B	0008290	cellular_component	F-actin capping protein complex
B	0010591	biological_process	regulation of lamellipodium assembly
B	0014069	cellular_component	postsynaptic density
B	0016020	cellular_component	membrane
B	0022604	biological_process	regulation of cell morphogenesis
B	0030018	cellular_component	Z disc
B	0030027	cellular_component	lamellipodium
B	0030030	biological_process	cell projection organization
B	0030032	biological_process	lamellipodium assembly
B	0030036	biological_process	actin cytoskeleton organization
B	0030863	cellular_component	cortical cytoskeleton
B	0031674	cellular_component	I band
B	0032279	cellular_component	asymmetric synapse
B	0051015	molecular_function	actin filament binding
B	0051016	biological_process	barbed-end actin filament capping
B	0051490	biological_process	negative regulation of filopodium assembly
B	0051693	biological_process	actin filament capping
B	0071203	cellular_component	WASH complex
B	0098685	cellular_component	Schaffer collateral - CA1 synapse
B	0120212	cellular_component	sperm head-tail coupling apparatus

Functional Information from PROSITE/UniProt

site_id	PS00231
Number of Residues	6
Details	F_ACTIN_CAPPING_BETA F-actin capping protein beta subunit signature. CDYNRD

Chain	Residue	Details
B	CYS62-ASP67

---

site_id	PS00748
Number of Residues	9
Details	F_ACTIN_CAPPING_A_1 F-actin capping protein alpha subunit signature 1. VHYYEDGNV

Chain	Residue	Details
A	VAL196-VAL204

---

site_id	PS00749
Number of Residues	11
Details	F_ACTIN_CAPPING_A_2 F-actin capping protein alpha subunit signature 2. KaLRRqLPVTR

Chain	Residue	Details
A	LYS256-ARG266

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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