3LGZ
Crystal structure of dehydrosqualene synthase Y129A from S. aureus complexed with presqualene pyrophosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016117 | biological_process | carotenoid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051996 | molecular_function | squalene synthase [NAD(P)H] activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE PS7 B 288 |
| Chain | Residue |
| B | HIS18 |
| B | VAL137 |
| B | ALA157 |
| B | LEU160 |
| B | LEU164 |
| B | GLN165 |
| B | ASN168 |
| B | ARG171 |
| B | TYR248 |
| B | ARG265 |
| B | MG290 |
| B | SER19 |
| B | HOH337 |
| B | HOH348 |
| B | PHE26 |
| B | TYR41 |
| B | CYS44 |
| B | ARG45 |
| B | ASP48 |
| B | VAL133 |
| B | ALA134 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 289 |
| Chain | Residue |
| B | ASN168 |
| B | ASP172 |
| B | HOH291 |
| B | HOH292 |
| B | HOH320 |
| B | HOH345 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG B 290 |
| Chain | Residue |
| B | PS7288 |
| B | HOH291 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18276850","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2ZCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3W7F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18276850","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2ZCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3W7F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18276850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3W7F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18276850","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2ZCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZCR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18276850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3W7F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18276850","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3W7F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
