3LGD
Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004000 | molecular_function | adenosine deaminase activity |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006154 | biological_process | adenosine catabolic process |
| A | 0019239 | molecular_function | deaminase activity |
| B | 0004000 | molecular_function | adenosine deaminase activity |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006154 | biological_process | adenosine catabolic process |
| B | 0019239 | molecular_function | deaminase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| A | GLU333 | |
| B | GLU333 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305 |
| Chain | Residue | Details |
| A | HIS358 | |
| B | HIS358 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS86 | |
| B | HIS86 | |
| B | HIS88 | |
| B | ASP89 | |
| B | TRP178 | |
| B | HIS267 | |
| B | GLY300 | |
| B | HIS330 | |
| B | ASP415 | |
| B | ASP416 | |
| A | HIS88 | |
| A | ASP89 | |
| A | TRP178 | |
| A | HIS267 | |
| A | GLY300 | |
| A | HIS330 | |
| A | ASP415 | |
| A | ASP416 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20147294 |
| Chain | Residue | Details |
| A | ASN101 | |
| A | ASN159 | |
| B | ASN101 | |
| B | ASN159 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN148 | |
| B | ASN148 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:20147294 |
| Chain | Residue | Details |
| A | ASN352 | |
| B | ASN352 |
