3L8K
Crystal structure of a dihydrolipoyl dehydrogenase from Sulfolobus solfataricus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004148 | molecular_function | dihydrolipoyl dehydrogenase (NADH) activity |
| A | 0006103 | biological_process | 2-oxoglutarate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004148 | molecular_function | dihydrolipoyl dehydrogenase (NADH) activity |
| B | 0006103 | biological_process | 2-oxoglutarate metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP A 465 |
| Chain | Residue |
| A | ILE8 |
| A | GLY39 |
| A | ASN40 |
| A | CYS41 |
| A | TYR108 |
| A | VAL109 |
| A | ALA137 |
| A | SER138 |
| A | GLY139 |
| A | ALA140 |
| A | GLY305 |
| A | GLY9 |
| A | ASP306 |
| A | HOH467 |
| A | HOH471 |
| A | HOH484 |
| A | GLY11 |
| A | GLY12 |
| A | ALA13 |
| A | ALA31 |
| A | ASP32 |
| A | PRO33 |
| A | LYS34 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 466 |
| Chain | Residue |
| A | ARG53 |
| A | GLN57 |
| A | ARG61 |
| A | VAL412 |
| A | HIS413 |
| A | GLN415 |
| A | TYR416 |
| A | HOH486 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP B 465 |
| Chain | Residue |
| B | ILE8 |
| B | GLY9 |
| B | GLY11 |
| B | GLY12 |
| B | ALA13 |
| B | ALA31 |
| B | ASP32 |
| B | PRO33 |
| B | LYS34 |
| B | GLY39 |
| B | ASN40 |
| B | CYS41 |
| B | TYR108 |
| B | VAL109 |
| B | ALA137 |
| B | SER138 |
| B | GLY139 |
| B | ALA140 |
| B | GLY305 |
| B | ASP306 |
| B | HOH467 |
| B | HOH470 |
| B | HOH471 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B 466 |
| Chain | Residue |
| B | ARG53 |
| B | GLN57 |
| B | ARG61 |
| B | VAL412 |
| B | HIS413 |
| B | GLN415 |
| B | HOH473 |
| B | HOH477 |
Functional Information from PROSITE/UniProt
| site_id | PS00076 |
| Number of Residues | 11 |
| Details | PYRIDINE_REDOX_1 Pyridine nucleotide-disulphide oxidoreductases class-I active site. GGnCLysGCVP |
| Chain | Residue | Details |
| A | GLY38-PRO48 |
