3L7Z

Crystal structure of the S. solfataricus archaeal exosome

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000177	cellular_component	cytoplasmic exosome (RNase complex)
A	0000178	cellular_component	exosome (RNase complex)
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006401	biological_process	RNA catabolic process
A	0016075	biological_process	rRNA catabolic process
A	0035925	molecular_function	mRNA 3'-UTR AU-rich region binding
B	0000175	molecular_function	3'-5'-RNA exonuclease activity
B	0000177	cellular_component	cytoplasmic exosome (RNase complex)
B	0000178	cellular_component	exosome (RNase complex)
B	0000956	biological_process	nuclear-transcribed mRNA catabolic process
B	0003723	molecular_function	RNA binding
B	0004518	molecular_function	nuclease activity
B	0004527	molecular_function	exonuclease activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006401	biological_process	RNA catabolic process
B	0010467	biological_process	gene expression
B	0016075	biological_process	rRNA catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
B	1902494	cellular_component	catalytic complex
C	0000178	cellular_component	exosome (RNase complex)
C	0000467	biological_process	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0005737	cellular_component	cytoplasm
C	0006401	biological_process	RNA catabolic process
C	0008143	molecular_function	poly(A) binding
C	0034475	biological_process	U4 snRNA 3'-end processing
C	0071034	biological_process	CUT catabolic process
C	0071051	biological_process	poly(A)-dependent snoRNA 3'-end processing
D	0000177	cellular_component	cytoplasmic exosome (RNase complex)
D	0000178	cellular_component	exosome (RNase complex)
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006401	biological_process	RNA catabolic process
D	0016075	biological_process	rRNA catabolic process
D	0035925	molecular_function	mRNA 3'-UTR AU-rich region binding
E	0000175	molecular_function	3'-5'-RNA exonuclease activity
E	0000177	cellular_component	cytoplasmic exosome (RNase complex)
E	0000178	cellular_component	exosome (RNase complex)
E	0000956	biological_process	nuclear-transcribed mRNA catabolic process
E	0003723	molecular_function	RNA binding
E	0004518	molecular_function	nuclease activity
E	0004527	molecular_function	exonuclease activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006401	biological_process	RNA catabolic process
E	0010467	biological_process	gene expression
E	0016075	biological_process	rRNA catabolic process
E	0016787	molecular_function	hydrolase activity
E	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
E	1902494	cellular_component	catalytic complex
F	0000178	cellular_component	exosome (RNase complex)
F	0000467	biological_process	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
F	0005737	cellular_component	cytoplasm
F	0006401	biological_process	RNA catabolic process
F	0008143	molecular_function	poly(A) binding
F	0034475	biological_process	U4 snRNA 3'-end processing
F	0071034	biological_process	CUT catabolic process
F	0071051	biological_process	poly(A)-dependent snoRNA 3'-end processing
G	0000177	cellular_component	cytoplasmic exosome (RNase complex)
G	0000178	cellular_component	exosome (RNase complex)
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0006401	biological_process	RNA catabolic process
G	0016075	biological_process	rRNA catabolic process
G	0035925	molecular_function	mRNA 3'-UTR AU-rich region binding
H	0000175	molecular_function	3'-5'-RNA exonuclease activity
H	0000177	cellular_component	cytoplasmic exosome (RNase complex)
H	0000178	cellular_component	exosome (RNase complex)
H	0000956	biological_process	nuclear-transcribed mRNA catabolic process
H	0003723	molecular_function	RNA binding
H	0004518	molecular_function	nuclease activity
H	0004527	molecular_function	exonuclease activity
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0006401	biological_process	RNA catabolic process
H	0010467	biological_process	gene expression
H	0016075	biological_process	rRNA catabolic process
H	0016787	molecular_function	hydrolase activity
H	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
H	1902494	cellular_component	catalytic complex
I	0000178	cellular_component	exosome (RNase complex)
I	0000467	biological_process	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
I	0005737	cellular_component	cytoplasm
I	0006401	biological_process	RNA catabolic process
I	0008143	molecular_function	poly(A) binding
I	0034475	biological_process	U4 snRNA 3'-end processing
I	0071034	biological_process	CUT catabolic process
I	0071051	biological_process	poly(A)-dependent snoRNA 3'-end processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 246

Chain	Residue
B	ALA133
B	GLY134
B	SER135
B	ARG136
B	ASP179

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 246

Chain	Residue
E	ASP179
E	ALA133
E	GLY134
E	SER135
E	ARG136

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 246

Chain	Residue
H	GLY134
H	SER135
H	ARG136
H	ASP179

---