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3L46

Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005085molecular_functionguanyl-nucleotide exchange factor activity
A0005096molecular_functionGTPase activator activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0043547biological_processpositive regulation of GTPase activity
A2000431biological_processregulation of cytokinesis, actomyosin contractile ring assembly
B0005085molecular_functionguanyl-nucleotide exchange factor activity
B0005096molecular_functionGTPase activator activity
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0043547biological_processpositive regulation of GTPase activity
B2000431biological_processregulation of cytokinesis, actomyosin contractile ring assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsModified residue: {"description":"Phosphothreonine; by PKC/PRKCI","evidences":[{"source":"PubMed","id":"21189248","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

244693

PDB entries from 2025-11-12

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