3KYH
Saccharomyces cerevisiae Cet1-Ceg1 capping apparatus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004651 | molecular_function | polynucleotide 5'-phosphatase activity |
| B | 0004651 | molecular_function | polynucleotide 5'-phosphatase activity |
| C | 0004484 | molecular_function | mRNA guanylyltransferase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| C | 0008033 | biological_process | tRNA processing |
| C | 0031533 | cellular_component | mRNA capping enzyme complex |
| C | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| D | 0004484 | molecular_function | mRNA guanylyltransferase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| D | 0008033 | biological_process | tRNA processing |
| D | 0031533 | cellular_component | mRNA capping enzyme complex |
| D | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for dimer formation"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"N6-GMP-lysine intermediate","evidences":[{"source":"PubMed","id":"8022828","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 486 |
| Chain | Residue | Details |
| A | GLU305 | metal ligand |
| A | GLU307 | metal ligand |
| A | ARG393 | electrostatic stabiliser |
| A | LYS409 | electrostatic stabiliser |
| A | LYS456 | electrostatic stabiliser |
| A | GLU496 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 486 |
| Chain | Residue | Details |
| B | GLU305 | metal ligand |
| B | GLU307 | metal ligand |
| B | ARG393 | electrostatic stabiliser |
| B | LYS409 | electrostatic stabiliser |
| B | LYS456 | electrostatic stabiliser |
| B | GLU496 | metal ligand |
