Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002682 | biological_process | regulation of immune system process |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006953 | biological_process | acute-phase response |
| A | 0006954 | biological_process | inflammatory response |
| A | 0031093 | cellular_component | platelet alpha granule lumen |
| A | 0032715 | biological_process | negative regulation of interleukin-6 production |
| A | 0032720 | biological_process | negative regulation of tumor necrosis factor production |
| A | 0032731 | biological_process | positive regulation of interleukin-1 beta production |
| A | 0032732 | biological_process | positive regulation of interleukin-1 production |
| A | 0032760 | biological_process | positive regulation of tumor necrosis factor production |
| A | 0035580 | cellular_component | specific granule lumen |
| A | 0062023 | cellular_component | collagen-containing extracellular matrix |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0072562 | cellular_component | blood microparticle |
| A | 1904724 | cellular_component | tertiary granule lumen |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE JIM A 193 |
| Chain | Residue |
| A | PHE49 |
| A | ILE88 |
| A | ARG90 |
| A | LEU112 |
| A | PHE114 |
| A | HOH297 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 194 |
| Chain | Residue |
| A | ALA144 |
| A | CYS5 |
| A | ALA6 |
| A | ASN7 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:4711474 |
| Chain | Residue | Details |
| A | PCA1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:15253437, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:22171320 |
| Chain | Residue | Details |
| A | ASN15 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:4603214 |
| Chain | Residue | Details |
| A | ASN38 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15253437, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19838169 |
| Chain | Residue | Details |
| A | ASN54 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:15253437, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:4603214 |
| Chain | Residue | Details |
| A | ASN75 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN85 |
