3KPB

Crystal Structure of the CBS domain pair of protein MJ0100 in complex with 5 -methylthioadenosine and S-adenosyl-L-methionine.

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE SAM A 1000

Chain	Residue
A	HOH58
A	ILE460
A	ASN479
A	ILE480
A	SER481
A	GLY482
A	HOH222
A	HOH320
A	ASN420
A	THR436
A	TRP438
A	ASP439
A	THR456
A	ASN458

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE SAM C 1000

Chain	Residue
C	HOH17
C	HOH146
C	THR436
C	TRP438
C	ASP439
C	THR456
C	ASN458
C	VAL459
C	ILE460
C	ILE480
C	SER481
C	GLY482
D	ASN418

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 5000

Chain	Residue
A	HOH152
B	HOH150
B	HOH244
B	ILE473
C	HOH223
C	GLY506

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 3000

Chain	Residue
B	VAL425
B	GLY429
B	ARG491
B	VAL492
D	HOH34
D	ARG491

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL B 4000

Chain	Residue
B	TRP438
C	LYS396

---

site_id	AC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE SAM D 1000

Chain	Residue
D	HOH1
D	HOH122
D	HOH229
D	HOH316
D	THR436
D	TRP438
D	ASP439
D	THR456
D	ASN458
D	VAL459
D	ILE460
D	ASN479
D	SER481
D	GLY482
D	HOH532

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL D 1101

Chain	Residue
C	HOH270
C	TYR489
C	ARG490
D	LEU431
D	ARG457
D	ASN458
D	VAL459
D	ARG490

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL D 1102

Chain	Residue
C	HOH260
C	LEU431
C	VAL432
C	ARG457
C	ASN458
C	VAL459
C	ARG490
D	TYR489
D	ARG490

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	224
Details	Domain: {"description":"CBS 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20026078","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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