3KH4

Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P6522 crystal form containing 6 chains in the asymmetric unit

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000302	biological_process	response to reactive oxygen species
A	0000303	biological_process	response to superoxide
A	0001541	biological_process	ovarian follicle development
A	0001819	biological_process	positive regulation of cytokine production
A	0001890	biological_process	placenta development
A	0001895	biological_process	retina homeostasis
A	0002262	biological_process	myeloid cell homeostasis
A	0004784	molecular_function	superoxide dismutase activity
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005759	cellular_component	mitochondrial matrix
A	0005777	cellular_component	peroxisome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006749	biological_process	glutathione metabolic process
A	0006801	biological_process	superoxide metabolic process
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006915	biological_process	apoptotic process
A	0006979	biological_process	response to oxidative stress
A	0007283	biological_process	spermatogenesis
A	0007566	biological_process	embryo implantation
A	0007605	biological_process	sensory perception of sound
A	0007626	biological_process	locomotory behavior
A	0008089	biological_process	anterograde axonal transport
A	0008090	biological_process	retrograde axonal transport
A	0008217	biological_process	regulation of blood pressure
A	0008270	molecular_function	zinc ion binding
A	0008340	biological_process	determination of adult lifespan
A	0009408	biological_process	response to heat
A	0009410	biological_process	response to xenobiotic stimulus
A	0010033	biological_process	response to organic substance
A	0010467	biological_process	gene expression
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0019226	biological_process	transmission of nerve impulse
A	0019228	biological_process	neuronal action potential
A	0019430	biological_process	removal of superoxide radicals
A	0030346	molecular_function	protein phosphatase 2B binding
A	0031267	molecular_function	small GTPase binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0032287	biological_process	peripheral nervous system myelin maintenance
A	0032839	cellular_component	dendrite cytoplasm
A	0032930	biological_process	positive regulation of superoxide anion generation
A	0032991	cellular_component	protein-containing complex
A	0033081	biological_process	regulation of T cell differentiation in thymus
A	0035234	biological_process	ectopic germ cell programmed cell death
A	0040014	biological_process	regulation of multicellular organism growth
A	0042542	biological_process	response to hydrogen peroxide
A	0042554	biological_process	superoxide anion generation
A	0042802	molecular_function	identical protein binding
A	0043025	cellular_component	neuronal cell body
A	0043065	biological_process	positive regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
A	0043085	biological_process	positive regulation of catalytic activity
A	0043087	biological_process	regulation of GTPase activity
A	0043410	biological_process	positive regulation of MAPK cascade
A	0043524	biological_process	negative regulation of neuron apoptotic process
A	0045471	biological_process	response to ethanol
A	0045541	biological_process	negative regulation of cholesterol biosynthetic process
A	0045859	biological_process	regulation of protein kinase activity
A	0046620	biological_process	regulation of organ growth
A	0046716	biological_process	muscle cell cellular homeostasis
A	0046872	molecular_function	metal ion binding
A	0048538	biological_process	thymus development
A	0048678	biological_process	response to axon injury
A	0050665	biological_process	hydrogen peroxide biosynthetic process
A	0050728	biological_process	negative regulation of inflammatory response
A	0050766	biological_process	positive regulation of phagocytosis
A	0051087	molecular_function	protein-folding chaperone binding
A	0051093	biological_process	negative regulation of developmental process
A	0051881	biological_process	regulation of mitochondrial membrane potential
A	0060047	biological_process	heart contraction
A	0060052	biological_process	neurofilament cytoskeleton organization
A	0060087	biological_process	relaxation of vascular associated smooth muscle
A	0060088	biological_process	auditory receptor cell stereocilium organization
A	0070062	cellular_component	extracellular exosome
A	0072593	biological_process	reactive oxygen species metabolic process
A	0099610	biological_process	action potential initiation
A	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
A	1904115	cellular_component	axon cytoplasm
A	2000242	biological_process	negative regulation of reproductive process
B	0000302	biological_process	response to reactive oxygen species
B	0000303	biological_process	response to superoxide
B	0001541	biological_process	ovarian follicle development
B	0001819	biological_process	positive regulation of cytokine production
B	0001890	biological_process	placenta development
B	0001895	biological_process	retina homeostasis
B	0002262	biological_process	myeloid cell homeostasis
B	0004784	molecular_function	superoxide dismutase activity
B	0005507	molecular_function	copper ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005758	cellular_component	mitochondrial intermembrane space
B	0005759	cellular_component	mitochondrial matrix
B	0005777	cellular_component	peroxisome
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006749	biological_process	glutathione metabolic process
B	0006801	biological_process	superoxide metabolic process
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006915	biological_process	apoptotic process
B	0006979	biological_process	response to oxidative stress
B	0007283	biological_process	spermatogenesis
B	0007566	biological_process	embryo implantation
B	0007605	biological_process	sensory perception of sound
B	0007626	biological_process	locomotory behavior
B	0008089	biological_process	anterograde axonal transport
B	0008090	biological_process	retrograde axonal transport
B	0008217	biological_process	regulation of blood pressure
B	0008270	molecular_function	zinc ion binding
B	0008340	biological_process	determination of adult lifespan
B	0009408	biological_process	response to heat
B	0009410	biological_process	response to xenobiotic stimulus
B	0010033	biological_process	response to organic substance
B	0010467	biological_process	gene expression
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0019226	biological_process	transmission of nerve impulse
B	0019228	biological_process	neuronal action potential
B	0019430	biological_process	removal of superoxide radicals
B	0030346	molecular_function	protein phosphatase 2B binding
B	0031267	molecular_function	small GTPase binding
B	0031410	cellular_component	cytoplasmic vesicle
B	0032287	biological_process	peripheral nervous system myelin maintenance
B	0032839	cellular_component	dendrite cytoplasm
B	0032930	biological_process	positive regulation of superoxide anion generation
B	0032991	cellular_component	protein-containing complex
B	0033081	biological_process	regulation of T cell differentiation in thymus
B	0035234	biological_process	ectopic germ cell programmed cell death
B	0040014	biological_process	regulation of multicellular organism growth
B	0042542	biological_process	response to hydrogen peroxide
B	0042554	biological_process	superoxide anion generation
B	0042802	molecular_function	identical protein binding
B	0043025	cellular_component	neuronal cell body
B	0043065	biological_process	positive regulation of apoptotic process
B	0043066	biological_process	negative regulation of apoptotic process
B	0043085	biological_process	positive regulation of catalytic activity
B	0043087	biological_process	regulation of GTPase activity
B	0043410	biological_process	positive regulation of MAPK cascade
B	0043524	biological_process	negative regulation of neuron apoptotic process
B	0045471	biological_process	response to ethanol
B	0045541	biological_process	negative regulation of cholesterol biosynthetic process
B	0045859	biological_process	regulation of protein kinase activity
B	0046620	biological_process	regulation of organ growth
B	0046716	biological_process	muscle cell cellular homeostasis
B	0046872	molecular_function	metal ion binding
B	0048538	biological_process	thymus development
B	0048678	biological_process	response to axon injury
B	0050665	biological_process	hydrogen peroxide biosynthetic process
B	0050728	biological_process	negative regulation of inflammatory response
B	0050766	biological_process	positive regulation of phagocytosis
B	0051087	molecular_function	protein-folding chaperone binding
B	0051093	biological_process	negative regulation of developmental process
B	0051881	biological_process	regulation of mitochondrial membrane potential
B	0060047	biological_process	heart contraction
B	0060052	biological_process	neurofilament cytoskeleton organization
B	0060087	biological_process	relaxation of vascular associated smooth muscle
B	0060088	biological_process	auditory receptor cell stereocilium organization
B	0070062	cellular_component	extracellular exosome
B	0072593	biological_process	reactive oxygen species metabolic process
B	0099610	biological_process	action potential initiation
B	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
B	1904115	cellular_component	axon cytoplasm
B	2000242	biological_process	negative regulation of reproductive process
C	0000302	biological_process	response to reactive oxygen species
C	0000303	biological_process	response to superoxide
C	0001541	biological_process	ovarian follicle development
C	0001819	biological_process	positive regulation of cytokine production
C	0001890	biological_process	placenta development
C	0001895	biological_process	retina homeostasis
C	0002262	biological_process	myeloid cell homeostasis
C	0004784	molecular_function	superoxide dismutase activity
C	0005507	molecular_function	copper ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005758	cellular_component	mitochondrial intermembrane space
C	0005759	cellular_component	mitochondrial matrix
C	0005777	cellular_component	peroxisome
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006749	biological_process	glutathione metabolic process
C	0006801	biological_process	superoxide metabolic process
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006915	biological_process	apoptotic process
C	0006979	biological_process	response to oxidative stress
C	0007283	biological_process	spermatogenesis
C	0007566	biological_process	embryo implantation
C	0007605	biological_process	sensory perception of sound
C	0007626	biological_process	locomotory behavior
C	0008089	biological_process	anterograde axonal transport
C	0008090	biological_process	retrograde axonal transport
C	0008217	biological_process	regulation of blood pressure
C	0008270	molecular_function	zinc ion binding
C	0008340	biological_process	determination of adult lifespan
C	0009408	biological_process	response to heat
C	0009410	biological_process	response to xenobiotic stimulus
C	0010033	biological_process	response to organic substance
C	0010467	biological_process	gene expression
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0019226	biological_process	transmission of nerve impulse
C	0019228	biological_process	neuronal action potential
C	0019430	biological_process	removal of superoxide radicals
C	0030346	molecular_function	protein phosphatase 2B binding
C	0031267	molecular_function	small GTPase binding
C	0031410	cellular_component	cytoplasmic vesicle
C	0032287	biological_process	peripheral nervous system myelin maintenance
C	0032839	cellular_component	dendrite cytoplasm
C	0032930	biological_process	positive regulation of superoxide anion generation
C	0032991	cellular_component	protein-containing complex
C	0033081	biological_process	regulation of T cell differentiation in thymus
C	0035234	biological_process	ectopic germ cell programmed cell death
C	0040014	biological_process	regulation of multicellular organism growth
C	0042542	biological_process	response to hydrogen peroxide
C	0042554	biological_process	superoxide anion generation
C	0042802	molecular_function	identical protein binding
C	0043025	cellular_component	neuronal cell body
C	0043065	biological_process	positive regulation of apoptotic process
C	0043066	biological_process	negative regulation of apoptotic process
C	0043085	biological_process	positive regulation of catalytic activity
C	0043087	biological_process	regulation of GTPase activity
C	0043410	biological_process	positive regulation of MAPK cascade
C	0043524	biological_process	negative regulation of neuron apoptotic process
C	0045471	biological_process	response to ethanol
C	0045541	biological_process	negative regulation of cholesterol biosynthetic process
C	0045859	biological_process	regulation of protein kinase activity
C	0046620	biological_process	regulation of organ growth
C	0046716	biological_process	muscle cell cellular homeostasis
C	0046872	molecular_function	metal ion binding
C	0048538	biological_process	thymus development
C	0048678	biological_process	response to axon injury
C	0050665	biological_process	hydrogen peroxide biosynthetic process
C	0050728	biological_process	negative regulation of inflammatory response
C	0050766	biological_process	positive regulation of phagocytosis
C	0051087	molecular_function	protein-folding chaperone binding
C	0051093	biological_process	negative regulation of developmental process
C	0051881	biological_process	regulation of mitochondrial membrane potential
C	0060047	biological_process	heart contraction
C	0060052	biological_process	neurofilament cytoskeleton organization
C	0060087	biological_process	relaxation of vascular associated smooth muscle
C	0060088	biological_process	auditory receptor cell stereocilium organization
C	0070062	cellular_component	extracellular exosome
C	0072593	biological_process	reactive oxygen species metabolic process
C	0099610	biological_process	action potential initiation
C	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
C	1904115	cellular_component	axon cytoplasm
C	2000242	biological_process	negative regulation of reproductive process
D	0000302	biological_process	response to reactive oxygen species
D	0000303	biological_process	response to superoxide
D	0001541	biological_process	ovarian follicle development
D	0001819	biological_process	positive regulation of cytokine production
D	0001890	biological_process	placenta development
D	0001895	biological_process	retina homeostasis
D	0002262	biological_process	myeloid cell homeostasis
D	0004784	molecular_function	superoxide dismutase activity
D	0005507	molecular_function	copper ion binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005758	cellular_component	mitochondrial intermembrane space
D	0005759	cellular_component	mitochondrial matrix
D	0005777	cellular_component	peroxisome
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006749	biological_process	glutathione metabolic process
D	0006801	biological_process	superoxide metabolic process
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006915	biological_process	apoptotic process
D	0006979	biological_process	response to oxidative stress
D	0007283	biological_process	spermatogenesis
D	0007566	biological_process	embryo implantation
D	0007605	biological_process	sensory perception of sound
D	0007626	biological_process	locomotory behavior
D	0008089	biological_process	anterograde axonal transport
D	0008090	biological_process	retrograde axonal transport
D	0008217	biological_process	regulation of blood pressure
D	0008270	molecular_function	zinc ion binding
D	0008340	biological_process	determination of adult lifespan
D	0009408	biological_process	response to heat
D	0009410	biological_process	response to xenobiotic stimulus
D	0010033	biological_process	response to organic substance
D	0010467	biological_process	gene expression
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0019226	biological_process	transmission of nerve impulse
D	0019228	biological_process	neuronal action potential
D	0019430	biological_process	removal of superoxide radicals
D	0030346	molecular_function	protein phosphatase 2B binding
D	0031267	molecular_function	small GTPase binding
D	0031410	cellular_component	cytoplasmic vesicle
D	0032287	biological_process	peripheral nervous system myelin maintenance
D	0032839	cellular_component	dendrite cytoplasm
D	0032930	biological_process	positive regulation of superoxide anion generation
D	0032991	cellular_component	protein-containing complex
D	0033081	biological_process	regulation of T cell differentiation in thymus
D	0035234	biological_process	ectopic germ cell programmed cell death
D	0040014	biological_process	regulation of multicellular organism growth
D	0042542	biological_process	response to hydrogen peroxide
D	0042554	biological_process	superoxide anion generation
D	0042802	molecular_function	identical protein binding
D	0043025	cellular_component	neuronal cell body
D	0043065	biological_process	positive regulation of apoptotic process
D	0043066	biological_process	negative regulation of apoptotic process
D	0043085	biological_process	positive regulation of catalytic activity
D	0043087	biological_process	regulation of GTPase activity
D	0043410	biological_process	positive regulation of MAPK cascade
D	0043524	biological_process	negative regulation of neuron apoptotic process
D	0045471	biological_process	response to ethanol
D	0045541	biological_process	negative regulation of cholesterol biosynthetic process
D	0045859	biological_process	regulation of protein kinase activity
D	0046620	biological_process	regulation of organ growth
D	0046716	biological_process	muscle cell cellular homeostasis
D	0046872	molecular_function	metal ion binding
D	0048538	biological_process	thymus development
D	0048678	biological_process	response to axon injury
D	0050665	biological_process	hydrogen peroxide biosynthetic process
D	0050728	biological_process	negative regulation of inflammatory response
D	0050766	biological_process	positive regulation of phagocytosis
D	0051087	molecular_function	protein-folding chaperone binding
D	0051093	biological_process	negative regulation of developmental process
D	0051881	biological_process	regulation of mitochondrial membrane potential
D	0060047	biological_process	heart contraction
D	0060052	biological_process	neurofilament cytoskeleton organization
D	0060087	biological_process	relaxation of vascular associated smooth muscle
D	0060088	biological_process	auditory receptor cell stereocilium organization
D	0070062	cellular_component	extracellular exosome
D	0072593	biological_process	reactive oxygen species metabolic process
D	0099610	biological_process	action potential initiation
D	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
D	1904115	cellular_component	axon cytoplasm
D	2000242	biological_process	negative regulation of reproductive process
E	0000302	biological_process	response to reactive oxygen species
E	0000303	biological_process	response to superoxide
E	0001541	biological_process	ovarian follicle development
E	0001819	biological_process	positive regulation of cytokine production
E	0001890	biological_process	placenta development
E	0001895	biological_process	retina homeostasis
E	0002262	biological_process	myeloid cell homeostasis
E	0004784	molecular_function	superoxide dismutase activity
E	0005507	molecular_function	copper ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005759	cellular_component	mitochondrial matrix
E	0005777	cellular_component	peroxisome
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006749	biological_process	glutathione metabolic process
E	0006801	biological_process	superoxide metabolic process
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006915	biological_process	apoptotic process
E	0006979	biological_process	response to oxidative stress
E	0007283	biological_process	spermatogenesis
E	0007566	biological_process	embryo implantation
E	0007605	biological_process	sensory perception of sound
E	0007626	biological_process	locomotory behavior
E	0008089	biological_process	anterograde axonal transport
E	0008090	biological_process	retrograde axonal transport
E	0008217	biological_process	regulation of blood pressure
E	0008270	molecular_function	zinc ion binding
E	0008340	biological_process	determination of adult lifespan
E	0009408	biological_process	response to heat
E	0009410	biological_process	response to xenobiotic stimulus
E	0010033	biological_process	response to organic substance
E	0010467	biological_process	gene expression
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0019226	biological_process	transmission of nerve impulse
E	0019228	biological_process	neuronal action potential
E	0019430	biological_process	removal of superoxide radicals
E	0030346	molecular_function	protein phosphatase 2B binding
E	0031267	molecular_function	small GTPase binding
E	0031410	cellular_component	cytoplasmic vesicle
E	0032287	biological_process	peripheral nervous system myelin maintenance
E	0032839	cellular_component	dendrite cytoplasm
E	0032930	biological_process	positive regulation of superoxide anion generation
E	0032991	cellular_component	protein-containing complex
E	0033081	biological_process	regulation of T cell differentiation in thymus
E	0035234	biological_process	ectopic germ cell programmed cell death
E	0040014	biological_process	regulation of multicellular organism growth
E	0042542	biological_process	response to hydrogen peroxide
E	0042554	biological_process	superoxide anion generation
E	0042802	molecular_function	identical protein binding
E	0043025	cellular_component	neuronal cell body
E	0043065	biological_process	positive regulation of apoptotic process
E	0043066	biological_process	negative regulation of apoptotic process
E	0043085	biological_process	positive regulation of catalytic activity
E	0043087	biological_process	regulation of GTPase activity
E	0043410	biological_process	positive regulation of MAPK cascade
E	0043524	biological_process	negative regulation of neuron apoptotic process
E	0045471	biological_process	response to ethanol
E	0045541	biological_process	negative regulation of cholesterol biosynthetic process
E	0045859	biological_process	regulation of protein kinase activity
E	0046620	biological_process	regulation of organ growth
E	0046716	biological_process	muscle cell cellular homeostasis
E	0046872	molecular_function	metal ion binding
E	0048538	biological_process	thymus development
E	0048678	biological_process	response to axon injury
E	0050665	biological_process	hydrogen peroxide biosynthetic process
E	0050728	biological_process	negative regulation of inflammatory response
E	0050766	biological_process	positive regulation of phagocytosis
E	0051087	molecular_function	protein-folding chaperone binding
E	0051093	biological_process	negative regulation of developmental process
E	0051881	biological_process	regulation of mitochondrial membrane potential
E	0060047	biological_process	heart contraction
E	0060052	biological_process	neurofilament cytoskeleton organization
E	0060087	biological_process	relaxation of vascular associated smooth muscle
E	0060088	biological_process	auditory receptor cell stereocilium organization
E	0070062	cellular_component	extracellular exosome
E	0072593	biological_process	reactive oxygen species metabolic process
E	0099610	biological_process	action potential initiation
E	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
E	1904115	cellular_component	axon cytoplasm
E	2000242	biological_process	negative regulation of reproductive process
F	0000302	biological_process	response to reactive oxygen species
F	0000303	biological_process	response to superoxide
F	0001541	biological_process	ovarian follicle development
F	0001819	biological_process	positive regulation of cytokine production
F	0001890	biological_process	placenta development
F	0001895	biological_process	retina homeostasis
F	0002262	biological_process	myeloid cell homeostasis
F	0004784	molecular_function	superoxide dismutase activity
F	0005507	molecular_function	copper ion binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005758	cellular_component	mitochondrial intermembrane space
F	0005759	cellular_component	mitochondrial matrix
F	0005777	cellular_component	peroxisome
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006749	biological_process	glutathione metabolic process
F	0006801	biological_process	superoxide metabolic process
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006915	biological_process	apoptotic process
F	0006979	biological_process	response to oxidative stress
F	0007283	biological_process	spermatogenesis
F	0007566	biological_process	embryo implantation
F	0007605	biological_process	sensory perception of sound
F	0007626	biological_process	locomotory behavior
F	0008089	biological_process	anterograde axonal transport
F	0008090	biological_process	retrograde axonal transport
F	0008217	biological_process	regulation of blood pressure
F	0008270	molecular_function	zinc ion binding
F	0008340	biological_process	determination of adult lifespan
F	0009408	biological_process	response to heat
F	0009410	biological_process	response to xenobiotic stimulus
F	0010033	biological_process	response to organic substance
F	0010467	biological_process	gene expression
F	0016209	molecular_function	antioxidant activity
F	0016491	molecular_function	oxidoreductase activity
F	0019226	biological_process	transmission of nerve impulse
F	0019228	biological_process	neuronal action potential
F	0019430	biological_process	removal of superoxide radicals
F	0030346	molecular_function	protein phosphatase 2B binding
F	0031267	molecular_function	small GTPase binding
F	0031410	cellular_component	cytoplasmic vesicle
F	0032287	biological_process	peripheral nervous system myelin maintenance
F	0032839	cellular_component	dendrite cytoplasm
F	0032930	biological_process	positive regulation of superoxide anion generation
F	0032991	cellular_component	protein-containing complex
F	0033081	biological_process	regulation of T cell differentiation in thymus
F	0035234	biological_process	ectopic germ cell programmed cell death
F	0040014	biological_process	regulation of multicellular organism growth
F	0042542	biological_process	response to hydrogen peroxide
F	0042554	biological_process	superoxide anion generation
F	0042802	molecular_function	identical protein binding
F	0043025	cellular_component	neuronal cell body
F	0043065	biological_process	positive regulation of apoptotic process
F	0043066	biological_process	negative regulation of apoptotic process
F	0043085	biological_process	positive regulation of catalytic activity
F	0043087	biological_process	regulation of GTPase activity
F	0043410	biological_process	positive regulation of MAPK cascade
F	0043524	biological_process	negative regulation of neuron apoptotic process
F	0045471	biological_process	response to ethanol
F	0045541	biological_process	negative regulation of cholesterol biosynthetic process
F	0045859	biological_process	regulation of protein kinase activity
F	0046620	biological_process	regulation of organ growth
F	0046716	biological_process	muscle cell cellular homeostasis
F	0046872	molecular_function	metal ion binding
F	0048538	biological_process	thymus development
F	0048678	biological_process	response to axon injury
F	0050665	biological_process	hydrogen peroxide biosynthetic process
F	0050728	biological_process	negative regulation of inflammatory response
F	0050766	biological_process	positive regulation of phagocytosis
F	0051087	molecular_function	protein-folding chaperone binding
F	0051093	biological_process	negative regulation of developmental process
F	0051881	biological_process	regulation of mitochondrial membrane potential
F	0060047	biological_process	heart contraction
F	0060052	biological_process	neurofilament cytoskeleton organization
F	0060087	biological_process	relaxation of vascular associated smooth muscle
F	0060088	biological_process	auditory receptor cell stereocilium organization
F	0070062	cellular_component	extracellular exosome
F	0072593	biological_process	reactive oxygen species metabolic process
F	0099610	biological_process	action potential initiation
F	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
F	1904115	cellular_component	axon cytoplasm
F	2000242	biological_process	negative regulation of reproductive process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU A 154

Chain	Residue
A	HIS46
A	HIS48
A	HIS63
A	HIS120

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 155

Chain	Residue
A	HIS63
A	HIS71
A	HIS80
A	ASP83
A	LYS136

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU B 154

Chain	Residue
B	HIS46
B	HIS48
B	HIS63
B	HIS120

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 155

Chain	Residue
B	HIS63
B	HIS71
B	HIS80
B	ASP83
B	LYS136

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU C 154

Chain	Residue
C	HIS46
C	HIS48
C	HIS63
C	HIS120

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 155

Chain	Residue
C	HIS63
C	HIS71
C	HIS80
C	ASP83
C	LYS136

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU D 154

Chain	Residue
D	HIS46
D	HIS48
D	HIS63
D	HIS120

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 155

Chain	Residue
D	HIS63
D	HIS71
D	HIS80
D	ASP83
D	LYS136

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU E 154

Chain	Residue
E	HIS46
E	HIS48
E	HIS63
E	HIS120

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN E 155

Chain	Residue
E	HIS63
E	HIS71
E	HIS80
E	ASP83
E	LYS136

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU F 154

Chain	Residue
F	HIS46
F	HIS48
F	HIS63
F	HIS120

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN F 155

Chain	Residue
F	HIS63
F	HIS71
F	HIS80
F	ASP83
F	LYS136

---

Functional Information from PROSITE/UniProt

site_id	PS00087
Number of Residues	11
Details	SOD_CU_ZN_1 Copper/Zinc superoxide dismutase signature 1. GFHVHEfGDnT

Chain	Residue	Details
A	GLY44-THR54

---

site_id	PS00332
Number of Residues	12
Details	SOD_CU_ZN_2 Copper/Zinc superoxide dismutase signature 2. GNAGsRlACgvI

Chain	Residue	Details
A	GLY138-ILE149

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000269|PubMed:12963370, ECO:0000269|PubMed:17548825

Chain	Residue	Details
A	HIS46
D	HIS46
D	HIS48
D	HIS120
E	HIS46
E	HIS48
E	HIS120
F	HIS46
F	HIS48
F	HIS120
A	HIS48
A	HIS120
B	HIS46
B	HIS48
B	HIS120
C	HIS46
C	HIS48
C	HIS120

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:20727846

Chain	Residue	Details
A	HIS63
C	HIS71
C	HIS80
C	ASP83
D	HIS63
D	HIS71
D	HIS80
D	ASP83
E	HIS63
E	HIS71
E	HIS80
A	HIS71
E	ASP83
F	HIS63
F	HIS71
F	HIS80
F	ASP83
A	HIS80
A	ASP83
B	HIS63
B	HIS71
B	HIS80
B	ASP83
C	HIS63

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: N-acetylalanine => ECO:0000269|PubMed:1463506, ECO:0000269|PubMed:7002610, ECO:0007744|PubMed:25944712

Chain	Residue	Details
A	ALA1
B	ALA1
C	ALA1
D	ALA1
E	ALA1
F	ALA1

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P08228

Chain	Residue	Details
A	LYS3
D	LYS3
D	LYS9
D	LYS91
E	LYS3
E	LYS9
E	LYS91
F	LYS3
F	LYS9
F	LYS91
A	LYS9
A	LYS91
B	LYS3
B	LYS9
B	LYS91
C	LYS3
C	LYS9
C	LYS91

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER98
B	SER98
C	SER98
D	SER98
E	SER98
F	SER98

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER102
B	SER102
C	SER102
D	SER102
E	SER102
F	SER102

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P07632

Chain	Residue	Details
A	SER105
B	SER105
C	SER105
D	SER105
E	SER105
F	SER105

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P08228

Chain	Residue	Details
A	SER107
B	SER107
C	SER107
D	SER107
E	SER107
F	SER107

---

site_id	SWS_FT_FI9
Number of Residues	6
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:24140062

Chain	Residue	Details
A	LYS122
B	LYS122
C	LYS122
D	LYS122
E	LYS122
F	LYS122

---

site_id	SWS_FT_FI10
Number of Residues	6
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P08228

Chain	Residue	Details
A	LYS136
B	LYS136
C	LYS136
D	LYS136
E	LYS136
F	LYS136

---

site_id	SWS_FT_FI11
Number of Residues	6
Details	LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:22496122

Chain	Residue	Details
A	CYS6
B	CYS6
C	CYS6
D	CYS6
E	CYS6
F	CYS6

---

site_id	SWS_FT_FI12
Number of Residues	12
Details	CROSSLNK: 1-(tryptophan-3-yl)-tryptophan (Trp-Trp) (interchain with W-33) => ECO:0000269|PubMed:20600836

Chain	Residue	Details
A	TRP32
F	TRP32
B	TRP32
C	TRP32
D	TRP32
E	TRP32

---