3KDF
X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free Expression
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000723 | biological_process | telomere maintenance |
| A | 0000724 | biological_process | double-strand break repair via homologous recombination |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003684 | molecular_function | damaged DNA binding |
| A | 0003697 | molecular_function | single-stranded DNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005662 | cellular_component | DNA replication factor A complex |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006289 | biological_process | nucleotide-excision repair |
| A | 0006298 | biological_process | mismatch repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0035861 | cellular_component | site of double-strand break |
| C | 0000723 | biological_process | telomere maintenance |
| C | 0000724 | biological_process | double-strand break repair via homologous recombination |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003684 | molecular_function | damaged DNA binding |
| C | 0003697 | molecular_function | single-stranded DNA binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005654 | cellular_component | nucleoplasm |
| C | 0005662 | cellular_component | DNA replication factor A complex |
| C | 0006260 | biological_process | DNA replication |
| C | 0006281 | biological_process | DNA repair |
| C | 0006284 | biological_process | base-excision repair |
| C | 0006289 | biological_process | nucleotide-excision repair |
| C | 0006298 | biological_process | mismatch repair |
| C | 0006310 | biological_process | DNA recombination |
| C | 0035861 | cellular_component | site of double-strand break |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 122 |
| Chain | Residue |
| A | LEU55 |
| A | MSE56 |
| A | GLU57 |
| A | CYS81 |
| A | HOH259 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 122 |
| Chain | Residue |
| C | GLN111 |
| C | PHE112 |
| C | HOH321 |
| A | GLU101 |
| A | HOH244 |
| C | ASP108 |
| C | PHE109 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 3 |
| Chain | Residue |
| C | GLN86 |
| C | PHE87 |
| C | LYS88 |
| D | GLU123 |
| D | THR124 |
| D | TYR125 |
| D | MSE152 |
| D | HOH175 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 123 |
| Chain | Residue |
| A | GLN86 |
| A | PHE87 |
| A | LYS88 |
| B | GLU123 |
| B | TYR125 |
| B | MSE152 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 7 |
| Chain | Residue |
| D | MSE147 |
| D | PRO148 |
| D | GLU150 |
| D | GLU154 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 123 |
| Chain | Residue |
| C | TYR84 |
| C | HOH414 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 124 |
| Chain | Residue |
| A | ASP108 |
| C | LYS104 |
| C | ASP108 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"26474068","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
