3KA8

Frog M-ferritin, EQH mutant, with cobalt

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CO A 176

Chain	Residue
A	HIS169
A	HOH342
A	HOH342
A	HOH342
A	HIS169
A	HIS169
A	HIS169
A	CL184
A	CL184
A	CL184
A	CL184
A	HOH342

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 177

Chain	Residue
A	GLU23
A	GLU58
A	HIS61
A	HOH363
A	HOH372

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 178

Chain	Residue
A	GLU57
A	GLU136
A	HIS140
A	HOH367
A	HOH384

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 179

Chain	Residue
A	HIS56
A	GLU60
A	GLU63
A	HOH233
A	HOH336
A	HOH502

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 180

Chain	Residue
A	HOH328
A	HOH328
A	HOH328
A	HOH360
A	HOH360
A	HOH360

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 181

Chain	Residue
A	HOH344
A	HOH344
A	HOH385
A	HOH385
A	HOH388
A	HOH388
A	HOH391
A	HOH391

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 182

Chain	Residue
A	HOH210
A	HOH210
A	HOH210
A	HOH499
A	HOH499
A	HOH499

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 183

Chain	Residue
A	SER10
A	HOH400
A	HOH434
A	HOH435
A	HOH468
A	HOH487

---

site_id	AC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CL A 184

Chain	Residue
A	LEU165
A	LEU165
A	LEU165
A	LEU165
A	HIS169
A	HIS169
A	HIS169
A	HIS169
A	CO176
A	CO176
A	CO176
A	CO176

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 185

Chain	Residue
A	HOH238
A	HOH264
A	HOH283
A	HOH304
A	HOH319

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 186

Chain	Residue
A	ARG5
A	ASN7
A	TYR8
A	HOH256
A	HOH294

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 187

Chain	Residue
A	SER10
A	HOH302

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 188

Chain	Residue
A	ASP87
A	GLU88

---

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 189

Chain	Residue
A	HIS45
A	HOH219
A	HOH324
A	HOH326
A	HOH327
A	HOH337
A	HOH338
A	HOH339

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 190

Chain	Residue
A	GLU132
A	TYR133
A	GLU135
A	GLU136

---

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 191

Chain	Residue
A	SER31
A	LYS52
A	ARG59

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 192

Chain	Residue
A	ASN91
A	GLU94
A	PRO157

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 193

Chain	Residue
A	HOH314
A	HOH334
A	HOH335
A	HOH409
A	HOH504
A	HOH281

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEseYLeeqvkhIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKFMkyQNkRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

---