3K96

2.1 Angstrom resolution crystal structure of glycerol-3-phosphate dehydrogenase (gpsA) from Coxiella burnetii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006072	biological_process	glycerol-3-phosphate metabolic process
A	0006650	biological_process	glycerophospholipid metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0046167	biological_process	glycerol-3-phosphate biosynthetic process
A	0046168	biological_process	glycerol-3-phosphate catabolic process
A	0046474	biological_process	glycerophospholipid biosynthetic process
A	0047952	molecular_function	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A	0051287	molecular_function	NAD binding
A	0141153	molecular_function	glycerol-3-phosphate dehydrogenase (NADP+) activity
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006072	biological_process	glycerol-3-phosphate metabolic process
B	0006650	biological_process	glycerophospholipid metabolic process
B	0008654	biological_process	phospholipid biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0046167	biological_process	glycerol-3-phosphate biosynthetic process
B	0046168	biological_process	glycerol-3-phosphate catabolic process
B	0046474	biological_process	glycerophospholipid biosynthetic process
B	0047952	molecular_function	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B	0051287	molecular_function	NAD binding
B	0141153	molecular_function	glycerol-3-phosphate dehydrogenase (NADP+) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BME B 401

Chain	Residue
B	SER38
B	ASP42
B	CYS67

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EPE B 402

Chain	Residue
B	GLN45
B	LYS64
B	TYR66
B	CYS67
B	ASP68
B	HOH481

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EPE A 403

Chain	Residue
A	GLN45
A	TYR66
A	CYS67
A	ASP68

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Functional Information from PROSITE/UniProt

site_id	PS00957
Number of Residues	22
Details	NAD_G3PDH NAD-dependent glycerol-3-phosphate dehydrogenase signature. GSVKNILAiAtGIsdGLkLGsN

Chain	Residue	Details
A	GLY189-ASN210

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00394

Chain	Residue	Details
A	LYS192
B	LYS192

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site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00394

Chain	Residue	Details
A	SER15
A	ARG256
A	ASN257
A	GLU282
B	SER15
B	TRP16
B	LYS110
B	GLY137
B	SER139
B	ALA141
B	LYS192
A	TRP16
B	ASP245
B	SER255
B	ARG256
B	ASN257
B	GLU282
A	LYS110
A	GLY137
A	SER139
A	ALA141
A	LYS192
A	ASP245
A	SER255

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1evy

Chain	Residue	Details
A	LYS192
A	THR249

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1evy

Chain	Residue	Details
B	LYS192
B	THR249

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