Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3K70

Crystal structure of the complete initiation complex of RecBCD

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0000724	biological_process	double-strand break repair via homologous recombination
B	0000725	biological_process	recombinational repair
B	0003677	molecular_function	DNA binding
B	0003678	molecular_function	DNA helicase activity
B	0004386	molecular_function	helicase activity
B	0004518	molecular_function	nuclease activity
B	0004520	molecular_function	DNA endonuclease activity
B	0004527	molecular_function	exonuclease activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006974	biological_process	DNA damage response
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0008854	molecular_function	exodeoxyribonuclease V activity
B	0009314	biological_process	response to radiation
B	0009338	cellular_component	exodeoxyribonuclease V complex
B	0015616	molecular_function	DNA translocase activity
B	0016787	molecular_function	hydrolase activity
B	0016853	molecular_function	isomerase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0032508	biological_process	DNA duplex unwinding
B	0043138	molecular_function	3'-5' DNA helicase activity
B	0044355	biological_process	clearance of foreign intracellular DNA
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0000725	biological_process	recombinational repair
C	0003677	molecular_function	DNA binding
C	0003678	molecular_function	DNA helicase activity
C	0004386	molecular_function	helicase activity
C	0004518	molecular_function	nuclease activity
C	0004527	molecular_function	exonuclease activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006974	biological_process	DNA damage response
C	0008854	molecular_function	exodeoxyribonuclease V activity
C	0009314	biological_process	response to radiation
C	0009338	cellular_component	exodeoxyribonuclease V complex
C	0016787	molecular_function	hydrolase activity
C	0032508	biological_process	DNA duplex unwinding
C	0044355	biological_process	clearance of foreign intracellular DNA
D	0000166	molecular_function	nucleotide binding
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0000725	biological_process	recombinational repair
D	0003677	molecular_function	DNA binding
D	0003678	molecular_function	DNA helicase activity
D	0004386	molecular_function	helicase activity
D	0004518	molecular_function	nuclease activity
D	0004527	molecular_function	exonuclease activity
D	0005524	molecular_function	ATP binding
D	0006281	biological_process	DNA repair
D	0006302	biological_process	double-strand break repair
D	0006310	biological_process	DNA recombination
D	0006974	biological_process	DNA damage response
D	0008854	molecular_function	exodeoxyribonuclease V activity
D	0009338	cellular_component	exodeoxyribonuclease V complex
D	0016787	molecular_function	hydrolase activity
D	0016853	molecular_function	isomerase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0017116	molecular_function	single-stranded DNA helicase activity
D	0032508	biological_process	DNA duplex unwinding
D	0043139	molecular_function	5'-3' DNA helicase activity
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0000724	biological_process	double-strand break repair via homologous recombination
E	0000725	biological_process	recombinational repair
E	0003677	molecular_function	DNA binding
E	0003678	molecular_function	DNA helicase activity
E	0004386	molecular_function	helicase activity
E	0004518	molecular_function	nuclease activity
E	0004520	molecular_function	DNA endonuclease activity
E	0004527	molecular_function	exonuclease activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005829	cellular_component	cytosol
E	0006281	biological_process	DNA repair
E	0006310	biological_process	DNA recombination
E	0006974	biological_process	DNA damage response
E	0008094	molecular_function	ATP-dependent activity, acting on DNA
E	0008854	molecular_function	exodeoxyribonuclease V activity
E	0009314	biological_process	response to radiation
E	0009338	cellular_component	exodeoxyribonuclease V complex
E	0015616	molecular_function	DNA translocase activity
E	0016787	molecular_function	hydrolase activity
E	0016853	molecular_function	isomerase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0032508	biological_process	DNA duplex unwinding
E	0043138	molecular_function	3'-5' DNA helicase activity
E	0044355	biological_process	clearance of foreign intracellular DNA
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0000724	biological_process	double-strand break repair via homologous recombination
F	0000725	biological_process	recombinational repair
F	0003677	molecular_function	DNA binding
F	0003678	molecular_function	DNA helicase activity
F	0004386	molecular_function	helicase activity
F	0004518	molecular_function	nuclease activity
F	0004527	molecular_function	exonuclease activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0006281	biological_process	DNA repair
F	0006310	biological_process	DNA recombination
F	0006974	biological_process	DNA damage response
F	0008854	molecular_function	exodeoxyribonuclease V activity
F	0009314	biological_process	response to radiation
F	0009338	cellular_component	exodeoxyribonuclease V complex
F	0016787	molecular_function	hydrolase activity
F	0032508	biological_process	DNA duplex unwinding
F	0044355	biological_process	clearance of foreign intracellular DNA
G	0000166	molecular_function	nucleotide binding
G	0000724	biological_process	double-strand break repair via homologous recombination
G	0000725	biological_process	recombinational repair
G	0003677	molecular_function	DNA binding
G	0003678	molecular_function	DNA helicase activity
G	0004386	molecular_function	helicase activity
G	0004518	molecular_function	nuclease activity
G	0004527	molecular_function	exonuclease activity
G	0005524	molecular_function	ATP binding
G	0006281	biological_process	DNA repair
G	0006302	biological_process	double-strand break repair
G	0006310	biological_process	DNA recombination
G	0006974	biological_process	DNA damage response
G	0008854	molecular_function	exodeoxyribonuclease V activity
G	0009338	cellular_component	exodeoxyribonuclease V complex
G	0016787	molecular_function	hydrolase activity
G	0016853	molecular_function	isomerase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0017116	molecular_function	single-stranded DNA helicase activity
G	0032508	biological_process	DNA duplex unwinding
G	0043139	molecular_function	5'-3' DNA helicase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 4000

Chain	Residue
B	HIS956
B	ASP1067
B	ASP1080
B	TYR1081
B	LYS1082

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA E 4000

Chain	Residue
E	HIS956
E	ASP1067
E	ASP1080
E	TYR1081

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	DNA_BIND: DNA_BIND => ECO:0000305

Chain	Residue	Details
D	GLN247
G	GLN247
B	SER560-ARG561
B	ARG761
E	ILE252-ARG254
E	VAL511-GLY512
E	SER560-ARG561
E	ARG761

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01487

Chain	Residue	Details
D	GLY171
G	GLY171

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01485, ECO:0000269\|PubMed:15538360

Chain	Residue	Details
B	ALA23
E	ALA23

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:15538360

Chain	Residue	Details
B	TRP447
E	TRP447

site_id	SWS_FT_FI5
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01485, ECO:0000305\|PubMed:15538360, ECO:0000305\|PubMed:18668125

Chain	Residue	Details
B	HIS956
B	ASP1067
B	ASP1080
E	HIS956
E	ASP1067
E	ASP1080

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000305\|PubMed:15538360, ECO:0000305\|PubMed:18668125

Chain	Residue	Details
B	TYR1081
E	TYR1081

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)