Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 901 |
| Chain | Residue |
| A | LYS14 |
| A | ILE15 |
| A | GLY16 |
| A | GLY17 |
| A | ILE63 |
| A | GLU65 |
| B | GLY17 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DMS A 100 |
| Chain | Residue |
| A | HOH1038 |
| B | LYS14 |
| B | ILE15 |
| B | GLY16 |
| B | GLY17 |
| B | ILE63 |
| A | GLY17 |
| A | DMS901 |
| site_id | AC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE ROC B 201 |
| Chain | Residue |
| A | ARG8 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | THR80 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH1041 |
| B | ARG8 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | THR80 |
| B | PRO81 |
| B | ILE84 |
| C | TRP6 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 801 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS C 901 |
| Chain | Residue |
| C | LYS14 |
| C | GLY17 |
| C | ILE63 |
| site_id | AC6 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE ROC D 201 |
| Chain | Residue |
| C | ARG8 |
| C | LEU23 |
| C | ASP25 |
| C | GLY27 |
| C | ALA28 |
| C | ASP29 |
| C | ASP30 |
| C | ILE47 |
| C | GLY48 |
| C | ILE50 |
| C | PRO81 |
| C | ILE84 |
| C | HOH1001 |
| D | ARG8 |
| D | LEU23 |
| D | ASP25 |
| D | GLY27 |
| D | ALA28 |
| D | ASP29 |
| D | ASP30 |
| D | VAL32 |
| D | GLY48 |
| D | GLY49 |
| D | ILE50 |
| D | THR80 |
| D | PRO81 |
| D | VAL82 |
| D | ILE84 |
| D | HOH1039 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS D 901 |
| Chain | Residue |
| C | GLY17 |
| C | DMS901 |
| D | LYS14 |
| D | ILE15 |
| D | GLY16 |
| D | GLY17 |
| D | ILE63 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| C | ALA22-ILE33 | |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| C | ASP25 | |
| D | ASP25 | |
| Chain | Residue | Details |
| C | PHE99 | |
| D | PHE99 | |
